Synnovis Analytics

Clinical Scientist

The closing date is 30 May 2025

Job summary

Applications are invited for a Clinical Scientist to join our dynamic team delivering neurological malignancy diagnostics. We are a highly specialised, national test directory compliant service that supports five surgical teams. We offer a wide breadth of molecular testing, from WGS to targeted assays including methylation arrays and NGS of RNA and DNA samples. There are opportunities for our scientists to participate in research studies and to attend complex MDTs including pathologists, oncologists and paediatricians.

Due to service expansion, we're now looking for a Clinical Scientist to join our close knit team. The post holder will participate in all aspects of the work carried out by the Molecular Neuropathology team which is an integral part of The Department of Clinical Neuropathology, located within King's College Hospital at Denmark Hill. The post holder is expected to liaise with clinicians, oncologists and neuropathologists responsible for treating patients both at King's and at our partner institutions within the London South Genomics network.

The post-holder will also have access to the Synnovis Scientific Learning and Development Fund, which aims to help fund further education and qualifications such as the FRCPath.

Applications will be considered from those close to registration.

Main duties of the job

The post holder will participate at a senior level in all aspects of the work of the Laboratory having a particular responsibility for the analysis and reporting of WGS data. The primary responsibility of the post holder is to analyse and report genetic data ensuring the timely delivery of the diagnostic service. In addition to this, the post holder will support the operations manager and consultant clinical scientist in the day to day delivery of the service and assist in the management and delivery of development work as directed. They will be expected to play a key role in the delivery of training, quality management and change control having strong skills in ICT and communication. They will have a wide knowledge of clinical molecular genetics, and will undertake continual professional development activities to keep up to date and help to ensure that the laboratory services are up to date with current scientific developments.

About us

Your development and learning

You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.

Through our Innovation Accelerator Fund, you can apply for finance to get that new innovative scientific project off the ground, and participate with the wider scientific community through symposiums, conferences and other peer group meetings.

Details

Date posted

16 May 2025

Pay scheme

Agenda for change

Band

Band 7

Salary

Depending on experience £55,613 to £62,460 per annum depending on experience

Contract

Permanent

Working pattern

Full-time

Reference number

J206-VIS6763

Job locations

King's College Hospital

Denmark Hill

London

SE5 9RS


Job description

Job responsibilities

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites however, from 1 April 2024 our people and services will start to move to our Hub laboratory in Blackfriars, Southwark, SE1, with some work remaining in refurbished essential services laboratories across our hospital network, focusing on the rapid turnover of urgent tests. Please do ask your recruiting manager if you wish to find out more.

Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.

The partnership provides services to 1.7 million people living in South East London, as well as to hundreds of thousands of patients from outside the region who use local healthcare services.

The partnership provides diagnostics, testing and digital pathology for hospital trusts, GP services and other healthcare providers.

Kings College Hospital Foundation Trust is one of the UKs leading NHS Foundation Trusts in specialist teaching. Kings has various divisions including Neurosciences, Haematology, Cancer and Cardiovascular sciences, where there are unlimited opportunities to develop and perfect your career.

Over the last 170 years, Kings has delivered nothing but world class service to all its patients from deprived communities as well as some of the wealthiest in London.

Communication

Participate in laboratory staff meetings and contribute to effective communication within the department relating to service issues, training needs and process changes

Clearly communicate development aims and outcomes to laboratory staff and to groups within the organisation. Communication at national and international meetings as directed

Act as a communication link between the bioinformatics team and the laboratory team ensuring both sides have a firm understanding of the processes and limitation of use

Provide and receive complex information relating to the clinical condition and treatment of patients and/or the results and interpretation of diagnostic tests to and from work colleagues or users of the service

Assess the clinical importance and urgency of test requests and results which impact on patient care and communicate these effectively to appropriate agencies

Prioritise and plan own workload within a given time period and communicate own work priorities within the team. Demonstrate flexibility in carrying out own work priorities within the team context

Liaise with users of the service as necessary, with direction of enquiries to the appropriate member of staff

Maintain courteous and professional conduct at all times with staff, patients and visitors.

Liaise with medical and laboratory staff at external referral centres regarding results and sample requirements

Technical

Assist in the development and establishment of new tests.

Be proactive in suggesting new technical developments and participate in the planning, development and implementation of these new developments

Liaise between the bioinformatics team, understanding the limitations of their knowledge around diagnostic services, and laboratory staff which may have limited knowledge and experience of bioinformatics processes

Provide a comprehensive and appropriate diagnostic service to users through the performance of manual, semi-automated and fully-automated laboratory investigations in accordance with Standard Operating Procedures

Ensure work is completed timely and to satisfactory standards, results are reported within the agreed turnaround times and in accordance with the relevant Standard Operating Procedure (SOP)

Monitor outstanding work lists and turnaround times of laboratory investigations and act on information to maintain and/or improve the service provided

Undertake technical validation of highly complex results from laboratory investigations where necessary using judgemental expertise and ensuring accuracy and precision as specified by laboratory protocols and quality procedures

To analyse samples from External Quality Assessment Schemes in a timely manner, communicate performance from this to the operations manager of the laboratory

Implement and maintain the Quality Assurance Procedures ensuring the ISO1589 standard is met and maintained

Assess, initiate and monitor appropriate action when a situation may cause service delivery failure

Review and revise laboratory SOP on a regular basis and advise the operations manager of any material changes

Scientific

Maintain registration with the Healthcare Professions Council (HCPC)

Maintain a portfolio that demonstrates CPD achievement and pass on knowledge to other staff where appropriate

  • In conjunction with the service delivery manager and the scientific lead develop, evaluate and implement new tests and processes including production or amendment of SOPs and provision and documentation of staff training

Undertake laboratory instrument evaluation as directed by the scientific lead and contribute to service development supported by evidence-based practice

Participate in research and development as directed

Understand how changes in the workflow will affect the delivery of a safe, robust high quality service for all users of the laboratory

Clinical

Understand the genotype/ phenotype relationship in depth with respect to at least two diseases reported by the laboratory

Participate in the signing out of clinical reports for conditions you have been assessed to be competent in

Assess the clinical relevance and importance of diagnostic test requests, work in progress and test results

Use interpretive skills to determine clinical significance of laboratory results and take appropriate action including:

Authorisation of laboratory investigations

Ordering relevant follow-up laboratory procedures

Adding relevant technical and clinically relevant comments

Referring results for second opinion

Informing the requestor/medical staff of clinically significant results

Efficient management of patients' clinical material and maintenance of a safe ethical system of storage

Provide approved departmental information and advice to other healthcare professionals, and refer on to appropriate specialists requests for information

Participate in audit to highlight deficiencies in the pre-examination, examination and post-examination process, as required by the operational manager

Laboratory Informatics

Comply with local and national policies for the safe, secure and confidential processing and storage of patient and other laboratory information

Be familiar with and proficient in the use of the Laboratory Information Systems (LIMS) in accordance with the relevant SOP's

Understand the laboratory data processing systems and their limitations

Be competent in the use of the Quality Management system ensuring all appropriate documentation is in date and recorded

Records are kept up to date and stored safely to ensure compliance with good work practices required for the ISO15189 standards

Maintain the integrity and accuracy of laboratory databases

Assist the operations manager to collect and monitor management and operational performance data including turnaround times, workload and materials consumption

Staff Management

Participate in the training of staff in the areas in which the post holder has been assessed as competent including laboratory instrumentation, new methodologies, units of the laboratory training program or other aspects of Healthcare Science as required

Participate in the work supervision and performance monitoring of less experienced State Registered Clinical Scientists, trainees and support staff ensuring that competency standards are maintained

In conjunction with the operations manager, set staff training objectives on rotation into the laboratory as defined by the requirements of the staff training record and appraisal needs

Perform skill, knowledge and conduct assessments of staff working in the area and ensure that the required competency standards are maintained

Contribute to a learning environment and facilitate the CPD of staff in conjunction with the operations manager/ scientific lead and Training and Quality Manager

Provide support and guidance and motivate staff to meet specified standards of performance in relation to their role, monitor their progress and undertake initial counselling as required

Job description

Job responsibilities

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites however, from 1 April 2024 our people and services will start to move to our Hub laboratory in Blackfriars, Southwark, SE1, with some work remaining in refurbished essential services laboratories across our hospital network, focusing on the rapid turnover of urgent tests. Please do ask your recruiting manager if you wish to find out more.

Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.

The partnership provides services to 1.7 million people living in South East London, as well as to hundreds of thousands of patients from outside the region who use local healthcare services.

The partnership provides diagnostics, testing and digital pathology for hospital trusts, GP services and other healthcare providers.

Kings College Hospital Foundation Trust is one of the UKs leading NHS Foundation Trusts in specialist teaching. Kings has various divisions including Neurosciences, Haematology, Cancer and Cardiovascular sciences, where there are unlimited opportunities to develop and perfect your career.

Over the last 170 years, Kings has delivered nothing but world class service to all its patients from deprived communities as well as some of the wealthiest in London.

Communication

Participate in laboratory staff meetings and contribute to effective communication within the department relating to service issues, training needs and process changes

Clearly communicate development aims and outcomes to laboratory staff and to groups within the organisation. Communication at national and international meetings as directed

Act as a communication link between the bioinformatics team and the laboratory team ensuring both sides have a firm understanding of the processes and limitation of use

Provide and receive complex information relating to the clinical condition and treatment of patients and/or the results and interpretation of diagnostic tests to and from work colleagues or users of the service

Assess the clinical importance and urgency of test requests and results which impact on patient care and communicate these effectively to appropriate agencies

Prioritise and plan own workload within a given time period and communicate own work priorities within the team. Demonstrate flexibility in carrying out own work priorities within the team context

Liaise with users of the service as necessary, with direction of enquiries to the appropriate member of staff

Maintain courteous and professional conduct at all times with staff, patients and visitors.

Liaise with medical and laboratory staff at external referral centres regarding results and sample requirements

Technical

Assist in the development and establishment of new tests.

Be proactive in suggesting new technical developments and participate in the planning, development and implementation of these new developments

Liaise between the bioinformatics team, understanding the limitations of their knowledge around diagnostic services, and laboratory staff which may have limited knowledge and experience of bioinformatics processes

Provide a comprehensive and appropriate diagnostic service to users through the performance of manual, semi-automated and fully-automated laboratory investigations in accordance with Standard Operating Procedures

Ensure work is completed timely and to satisfactory standards, results are reported within the agreed turnaround times and in accordance with the relevant Standard Operating Procedure (SOP)

Monitor outstanding work lists and turnaround times of laboratory investigations and act on information to maintain and/or improve the service provided

Undertake technical validation of highly complex results from laboratory investigations where necessary using judgemental expertise and ensuring accuracy and precision as specified by laboratory protocols and quality procedures

To analyse samples from External Quality Assessment Schemes in a timely manner, communicate performance from this to the operations manager of the laboratory

Implement and maintain the Quality Assurance Procedures ensuring the ISO1589 standard is met and maintained

Assess, initiate and monitor appropriate action when a situation may cause service delivery failure

Review and revise laboratory SOP on a regular basis and advise the operations manager of any material changes

Scientific

Maintain registration with the Healthcare Professions Council (HCPC)

Maintain a portfolio that demonstrates CPD achievement and pass on knowledge to other staff where appropriate

  • In conjunction with the service delivery manager and the scientific lead develop, evaluate and implement new tests and processes including production or amendment of SOPs and provision and documentation of staff training

Undertake laboratory instrument evaluation as directed by the scientific lead and contribute to service development supported by evidence-based practice

Participate in research and development as directed

Understand how changes in the workflow will affect the delivery of a safe, robust high quality service for all users of the laboratory

Clinical

Understand the genotype/ phenotype relationship in depth with respect to at least two diseases reported by the laboratory

Participate in the signing out of clinical reports for conditions you have been assessed to be competent in

Assess the clinical relevance and importance of diagnostic test requests, work in progress and test results

Use interpretive skills to determine clinical significance of laboratory results and take appropriate action including:

Authorisation of laboratory investigations

Ordering relevant follow-up laboratory procedures

Adding relevant technical and clinically relevant comments

Referring results for second opinion

Informing the requestor/medical staff of clinically significant results

Efficient management of patients' clinical material and maintenance of a safe ethical system of storage

Provide approved departmental information and advice to other healthcare professionals, and refer on to appropriate specialists requests for information

Participate in audit to highlight deficiencies in the pre-examination, examination and post-examination process, as required by the operational manager

Laboratory Informatics

Comply with local and national policies for the safe, secure and confidential processing and storage of patient and other laboratory information

Be familiar with and proficient in the use of the Laboratory Information Systems (LIMS) in accordance with the relevant SOP's

Understand the laboratory data processing systems and their limitations

Be competent in the use of the Quality Management system ensuring all appropriate documentation is in date and recorded

Records are kept up to date and stored safely to ensure compliance with good work practices required for the ISO15189 standards

Maintain the integrity and accuracy of laboratory databases

Assist the operations manager to collect and monitor management and operational performance data including turnaround times, workload and materials consumption

Staff Management

Participate in the training of staff in the areas in which the post holder has been assessed as competent including laboratory instrumentation, new methodologies, units of the laboratory training program or other aspects of Healthcare Science as required

Participate in the work supervision and performance monitoring of less experienced State Registered Clinical Scientists, trainees and support staff ensuring that competency standards are maintained

In conjunction with the operations manager, set staff training objectives on rotation into the laboratory as defined by the requirements of the staff training record and appraisal needs

Perform skill, knowledge and conduct assessments of staff working in the area and ensure that the required competency standards are maintained

Contribute to a learning environment and facilitate the CPD of staff in conjunction with the operations manager/ scientific lead and Training and Quality Manager

Provide support and guidance and motivate staff to meet specified standards of performance in relation to their role, monitor their progress and undertake initial counselling as required

Person Specification

Qualifications

Essential

  • Degree in a scientific discipline
  • State registration as Clinical Scientist with HCPC or close to registration.

Desirable

  • Higher scientific degree

Experience

Essential

  • Significant experience in a molecular diagnostic laboratory
  • Experience of molecular genetic reporting
  • Experience of working with next generation sequencing technology

Desirable

  • Involvement in the development of a new assay or implementation of a new piece of equipment

Skills & Knowledge

Essential

  • Competent in variant classification/reporting
  • Good verbal and written communication skills in English
  • Quality Management and Audit

Desirable

  • Experience of liquid handling robots for the automation of laboratory testing
  • Able to respond to changes in workload and solve problems with the minimum of help
  • Comprehensive molecular diagnostic theory
Person Specification

Qualifications

Essential

  • Degree in a scientific discipline
  • State registration as Clinical Scientist with HCPC or close to registration.

Desirable

  • Higher scientific degree

Experience

Essential

  • Significant experience in a molecular diagnostic laboratory
  • Experience of molecular genetic reporting
  • Experience of working with next generation sequencing technology

Desirable

  • Involvement in the development of a new assay or implementation of a new piece of equipment

Skills & Knowledge

Essential

  • Competent in variant classification/reporting
  • Good verbal and written communication skills in English
  • Quality Management and Audit

Desirable

  • Experience of liquid handling robots for the automation of laboratory testing
  • Able to respond to changes in workload and solve problems with the minimum of help
  • Comprehensive molecular diagnostic theory

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Synnovis Analytics

Address

King's College Hospital

Denmark Hill

London

SE5 9RS


Employer's website

http://www.synnovis.co.uk/ (Opens in a new tab)

Employer details

Employer name

Synnovis Analytics

Address

King's College Hospital

Denmark Hill

London

SE5 9RS


Employer's website

http://www.synnovis.co.uk/ (Opens in a new tab)

Employer contact details

For questions about the job, contact:

Principal Clinical Scientist

Kelly Eggleton

kelly.eggleton@nhs.net

Details

Date posted

16 May 2025

Pay scheme

Agenda for change

Band

Band 7

Salary

Depending on experience £55,613 to £62,460 per annum depending on experience

Contract

Permanent

Working pattern

Full-time

Reference number

J206-VIS6763

Job locations

King's College Hospital

Denmark Hill

London

SE5 9RS


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