Job summary
The Genetics department is looking for enthusiastic, highly motivated Genetics Technologists to join our comprehensive Genetics Service at the South East Genomic Laboratory Hub (SEGLH), based at Guy's Hospital. You will support the continued provision of service and development of new tests aligned to the NHSE Genetics Test Directory.
We are recruiting to permanent posts within the Monogenics technical team which provides testing of single gene disorders, including WGS.
The ideal candidates will be quick learners and good team players. This laboratory based role will give you the job satisfaction that comes from knowing that no two days are the same.The successful candidate will perform a variety of routine and complex genetic diagnostic tests, including analysis of Sanger sequencing and genotyping data, with minimal supervision. Practical experience in a broad range of genetic techniques as well as previous experience in a diagnostic laboratory is desirable.
The post holders are expected to maintain professional competency and dexterity in precision based tasks, and maintain the levels of concentration required to maintain quality service.
Main duties of the job
The post holders will undertake a range of laboratory and housekeeping duties as appropriate, making use of the laboratory robotics equipment. They will work as part of a team, comprising of MLAs and Genetics Technologists, who are line managed by Senior Technical staff.
The technical and scientific teams work closely to deliver a high-quality laboratory diagnostic service. Excellent communication skills are required to work effectively with other team members.
They will perform semi-automated and manual processing of specimens which requires a high level of dexterity.
They will also ensure quality control measures are carried out to monitor analytical performance, take corrective action where applicable and report any failures to a senior members of staff.
The post holder will ensure standards as required by the ISO15189 are maintained.
About us
The Genetics laboratories are part of Synnovis Analytics and are located within the Guy's Hospital site. The Genetics department is made up of more than 120 staff and with close links to Clinical Services throughout Guy's and St Thomas' NHS Foundation Trust (GSTfT) and St George's Hospital Foundation Trust.
With our partner laboratories, the GLH for the South London region provides a comprehensive genomics service for a population of 8 million which includes specialist germline and cancer tests and a class-leading whole exome sequencing service.
The laboratory works collaboratively with other pathology disciplines and research groups such as GSTfT Biomedical Research Centre and Genomics Innovation Unit and the GSTfT Assisted Conception Unit for Preimplantation Genetic Diagnosis.
Your development and learning
You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.
Through our Innovation Accelerator Fund, you can apply for finance to get that new innovative scientific project off the ground, and participate with the wider scientific community through symposiums, conferences and other peer group meetings.
Job description
Job responsibilities
Experience of handling clinical samples and use of pipettes is essential.
The post holders will be responsible for:
- Performing PCR, MLPA, Sanger sequencing, next generation sequencing as indicated to generate data. Analyse data and write reports as directed in collaboration with clinical scientist colleagues.
- They will perform automated, semi-automated and manual processing of specimens which may require a high level of dexterity.
- They will also ensure quality control measures are carried out to monitor analytical performance, take corrective action where applicable and report any failures to a senior member of staff.
- Adherence to the laboratory standard operating procedures.
- Strict adherence to the laboratory and Departmental Health & Safety regulations and Codes of Practice.
- Undertaking work to ensure that all results are reported within agreed turnaround times and resolve any problems associated with incomplete results
Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.
The partnership provides services to 1.7 million people living in South East London, as well as to hundreds of thousands of patients from outside the region who use local healthcare services.
The partnership provides diagnostics, testing and digital pathology for hospital trusts, GP services and other healthcare providers.
Guys and St Thomas Hospital Foundation Trust is a major emergency and specialist teaching Trust which has all the specialties associated with a fascinating and career defining case load including: Womens Services, Fetal Medicine, Haematology, Oncology, Transplantation, and is also home to the Evelina Childrens Hospital and the Cancer Centre on the Guys site.
You will be close to the vibrant Borough Market and the South Bank, which are exceptional London locations; perfect places to work and relax next to such iconic venues as Big Ben, The London Eye and The Shard!
Job description
Job responsibilities
Experience of handling clinical samples and use of pipettes is essential.
The post holders will be responsible for:
- Performing PCR, MLPA, Sanger sequencing, next generation sequencing as indicated to generate data. Analyse data and write reports as directed in collaboration with clinical scientist colleagues.
- They will perform automated, semi-automated and manual processing of specimens which may require a high level of dexterity.
- They will also ensure quality control measures are carried out to monitor analytical performance, take corrective action where applicable and report any failures to a senior member of staff.
- Adherence to the laboratory standard operating procedures.
- Strict adherence to the laboratory and Departmental Health & Safety regulations and Codes of Practice.
- Undertaking work to ensure that all results are reported within agreed turnaround times and resolve any problems associated with incomplete results
Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.
The partnership provides services to 1.7 million people living in South East London, as well as to hundreds of thousands of patients from outside the region who use local healthcare services.
The partnership provides diagnostics, testing and digital pathology for hospital trusts, GP services and other healthcare providers.
Guys and St Thomas Hospital Foundation Trust is a major emergency and specialist teaching Trust which has all the specialties associated with a fascinating and career defining case load including: Womens Services, Fetal Medicine, Haematology, Oncology, Transplantation, and is also home to the Evelina Childrens Hospital and the Cancer Centre on the Guys site.
You will be close to the vibrant Borough Market and the South Bank, which are exceptional London locations; perfect places to work and relax next to such iconic venues as Big Ben, The London Eye and The Shard!
Person Specification
Qualifications
Essential
- BSc in relevant scientific discipline or equivalent
Desirable
Experience
Essential
- Experience of handling of clinical samples.
- Practical experience in a range of molecular laboratory techniques including PCR and Sanger sequencing.
Desirable
- Previous work within a genetics laboratory
- Previous experience of preparing samples for Next Generation Sequencing (NGS
Skills and Knowledge
Essential
- Knowledge of genetic diseases and theoretical aspects of molecular genetic diagnostic tests
Desirable
Person Specification
Qualifications
Essential
- BSc in relevant scientific discipline or equivalent
Desirable
Experience
Essential
- Experience of handling of clinical samples.
- Practical experience in a range of molecular laboratory techniques including PCR and Sanger sequencing.
Desirable
- Previous work within a genetics laboratory
- Previous experience of preparing samples for Next Generation Sequencing (NGS
Skills and Knowledge
Essential
- Knowledge of genetic diseases and theoretical aspects of molecular genetic diagnostic tests
Desirable
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.