Job summary
**Important**
Please apply for this post via the Cardiff University website only www.cardiff.ac.uk/jobs and search for vacancy number 16173BR.
This is a rare opportunity to join a new and exciting research initiative with Cardiff University, Velindre University NHS Trust and Cardiff and Vale UHB in the emerging Cardiff Cancer Research Hub. Our aim is to work across organisations to deliver translational and clinical research creating close working relationships between clinicians and scientists. Working with both our pre-clinical and clinically orientated teams, the role will include applying genomics-guided approaches to understand the biology of cancer and develop targeted, effective, and less-toxic therapies to be brought to patients.
Cardiff University is in the process of developing Advanced Treatments such as Oncolytic Vaccines and Cellular Based therapies as well as small molecules for the selective targeting of tumour cells. This drug development research will be supported by a genomics-guided precision medicine approach based on increased understanding of alterations in cancer genomes.
This post is full-time (37 hours per week), open-ended, and available immediately.
Please see full Job Description in supporting documents.
Main duties of the job
Job Purpose
To conduct clinical research in Cancer Genomics within Cardiff University laboratories and our oncology trial research team to contribute to the overall research performance of Velindre and Cardiff University. To carry out research contributing to improvements in delivery of early and late phase oncology clinical trials leading to the publishing of work in national and international journals, pursue excellence in research, teaching and enterprise, and to inspire others to do the same. There is no initial service delivery component to the post so that the successful candidate would be able to focus their time entirely on research activity.
About us
Working at Cardiff University offers you competitive remuneration, an impressive array of benefits, excellent career development and a positive working environment.
We are one of the UKs most innovative, ambitious, and successful universities and recognise that our success depends largely upon the commitment, energy and enthusiasm of our people.
That's why we strive to provide excellent working conditions and policies for our staff, with benefits ranging from generous leave entitlement to training and development opportunities.
We are committed to supporting and promoting equality and diversity. Our inclusive environment welcomes applications from talented people from diverse backgrounds.
Join us and help us achieve our ambition of becoming a world-leading, research-excellent, educationally outstanding university, driven by creativity and curiosity, which fulfils its social, cultural and economic obligations to Cardiff, Wales, and the world.
Job description
Job responsibilities
Main Duties and Responsibilities
Research
- You will be expected to lead and develop internationally excellent research activity in Clinical Cancer Genomics within the overall agreed research strategies of the Division of Cancer and Genetics, School of Medicine, College of Biomedical and Life Sciences, and University
- To generate and pursue independent and original clinical trial ideas through interactions with pre-clinical scientists in Cardiff, Wales and through participation in the Experimental Cancer Medicine Centre (ECMC), Wales Cancer Research Centre (WCRC), Velindre Cancer Centre, Genomic Partnership Wales (GPW), Wales Gene Park (WGP) and All-Wales Medical Genomics Service (AWMGS)
- To disseminate research findings using appropriate and effective publications, presentations at national/international meetings and conferences, and research seminars
- To prepare external funding applications as well as research ethics and research governance applications as appropriate, and publish results arising from it in peer-reviewed international academic journals
- To contribute through new research and research-funding initiatives to the School of Medicines Research Excellence Framework strategy, through publication of 3* and 4* outputs, and potential impact
- To become familiar with trial protocols and working practice within Velindre Cancer Centre (VCC), participate in oncology patient management in early phase clinical trials, promote unifying working practice in clinical trial delivery between VCC trials unit and UHW and perform duties at both sites
- To act as supervisor/co-supervisor for postgraduate research (PGR) students including masters and doctoral students, working as part of an approved training programme
- To contribute to PGR progress monitoring as chair or member of review panels
Teaching
- Demonstrate academic leadership, both in terms of organisation and delivery, of clinical and research education, including in undergraduate teaching and postgraduate training programmes
- To contribute to undergraduate medical teaching in the School of Medicine as set out by the College of Biomedical and Life Sciences (BLS) and the forthcoming School of Medicine Teaching Charter (the precise level will be commensurate with the FTE appointment and concurrent Academic/Leadership duties)
- To undertake work associated with examinations, such as setting and marking assessments and providing student feedback
- To provide specialist lectures for the undergraduate medical curriculum
- To lecture and act as project supervisor for BSc Intercalated students
- To act as project supervisor for Student Selected Component (SSC) projects
- To act as a Personal Tutor and provide academic advice and pastoral support to students
Clinical
- To hold and maintain a Licence to Practise with the General Medical Council
- To hold an honorary consultant contract with the relevant NHS Trust(s) and Health Boards
- To provide Direct Clinical Care and Supporting Professional Activities, in line with the provisions of the amended Consultant Contract for Wales
- To provide a consultant-led metastatic breast cancer service at Velindre Cancer Centre, working with other multidisciplinary colleagues, as agreed with the Clinical Director of Velindre Cancer Centre, via the Job Planning process.
- To provide, with multidisciplinary colleagues, a cancer genetics service to patients and families from South East Wales, agreed with the Clinical Director of the AWMGS, via the job planning process
- To lead on developments in Breast Cancer genomics/genetics and tumour biology at Velindre Cancer Centre and contribute to horizon scanning and service development in this area.
- The post-holder will not be required to participate in the consultant acute oncology on-call rota but would review any team inpatients as necessary
- Provide virtual advice and to liaise with other health care providers, hospitals and primary care teams, as required
- To undertake the professional supervision and management of junior staff - in certain circumstances, the post-holder may be named as the clinical supervisor for junior staff
- To participate actively in clinical audit, in liaison with other colleagues and in line with the NHS Trust policy on the implementation of clinical governance
- To participate actively in Continuing Professional Development, in line with guidance from the Royal College of Physicians and in agreement with the Chief Executive of the relevant NHS Trust(s)
Other
- To engage effectively with industrial, commercial, and public sector organisations, charities, professional institutions, and other academic institutions, regionally and nationally to raise awareness of Cardiff Universitys and AWMGSs profile, to cultivate strategically valuable alliances, and to pursue opportunities for collaboration across a range of activities - these activities are expected to contribute to AWMGS and the enhancement of its regional and national profile
- To undergo personal and professional development that is appropriate to, and which will enhance performance
- To support and promote the Genomic Research Strategy in Wales, Wales Cancer Research Strategy and the Cardiff University Strategy
- To engage with Genomic Partnership Wales and its stakeholders, including patient and public representatives and patients to develop and promote genomic research - the role will specifically require engagement with clinicians from cancer centres across Wales, Centre for Trials Research and scientists within Cardiff University
- To participate in School of Medicine administration and activities to promote the School and its work to the wider University and the outside world
- Any other duties not included above, but consistent with the role
The post holder will also be expected to:
- Maintain scientific competency by attending relevant lectures, courses, seminars and conferences
- Contribute to the effective management of the Division, School and Research Theme at College, within the University
- Provide leadership that ensures Tripartite Collaboration between Cardiff and Vale; Cardiff University and Velindre
- Ensure compliance with legal and regulatory requirements in respect of equality and diversity, data protection, copyright and licensing, security, financial and other University policies, procedures and codes as appropriate
- Perform other academic duties, on an occasional basis, and by agreement, which are not included above, but which are consistent with the role
The post holder will be required to actively participate in, and comply fully with, the clinical academic/NHS Joint Appraisal Process and the requirements for consultant revalidation. The required arrangements are in place, as laid down by the Royal College of Physicians, to ensure that all doctors have an annual appraisal with a trained appraiser and supports clinical academic staff going through the revalidation process. Cardiff and Vale UHB will be the host organisation for revalidation.
A job plan will be agreed at appointment, please see provisional job plan in the full job description in supporting documents.
Job description
Job responsibilities
Main Duties and Responsibilities
Research
- You will be expected to lead and develop internationally excellent research activity in Clinical Cancer Genomics within the overall agreed research strategies of the Division of Cancer and Genetics, School of Medicine, College of Biomedical and Life Sciences, and University
- To generate and pursue independent and original clinical trial ideas through interactions with pre-clinical scientists in Cardiff, Wales and through participation in the Experimental Cancer Medicine Centre (ECMC), Wales Cancer Research Centre (WCRC), Velindre Cancer Centre, Genomic Partnership Wales (GPW), Wales Gene Park (WGP) and All-Wales Medical Genomics Service (AWMGS)
- To disseminate research findings using appropriate and effective publications, presentations at national/international meetings and conferences, and research seminars
- To prepare external funding applications as well as research ethics and research governance applications as appropriate, and publish results arising from it in peer-reviewed international academic journals
- To contribute through new research and research-funding initiatives to the School of Medicines Research Excellence Framework strategy, through publication of 3* and 4* outputs, and potential impact
- To become familiar with trial protocols and working practice within Velindre Cancer Centre (VCC), participate in oncology patient management in early phase clinical trials, promote unifying working practice in clinical trial delivery between VCC trials unit and UHW and perform duties at both sites
- To act as supervisor/co-supervisor for postgraduate research (PGR) students including masters and doctoral students, working as part of an approved training programme
- To contribute to PGR progress monitoring as chair or member of review panels
Teaching
- Demonstrate academic leadership, both in terms of organisation and delivery, of clinical and research education, including in undergraduate teaching and postgraduate training programmes
- To contribute to undergraduate medical teaching in the School of Medicine as set out by the College of Biomedical and Life Sciences (BLS) and the forthcoming School of Medicine Teaching Charter (the precise level will be commensurate with the FTE appointment and concurrent Academic/Leadership duties)
- To undertake work associated with examinations, such as setting and marking assessments and providing student feedback
- To provide specialist lectures for the undergraduate medical curriculum
- To lecture and act as project supervisor for BSc Intercalated students
- To act as project supervisor for Student Selected Component (SSC) projects
- To act as a Personal Tutor and provide academic advice and pastoral support to students
Clinical
- To hold and maintain a Licence to Practise with the General Medical Council
- To hold an honorary consultant contract with the relevant NHS Trust(s) and Health Boards
- To provide Direct Clinical Care and Supporting Professional Activities, in line with the provisions of the amended Consultant Contract for Wales
- To provide a consultant-led metastatic breast cancer service at Velindre Cancer Centre, working with other multidisciplinary colleagues, as agreed with the Clinical Director of Velindre Cancer Centre, via the Job Planning process.
- To provide, with multidisciplinary colleagues, a cancer genetics service to patients and families from South East Wales, agreed with the Clinical Director of the AWMGS, via the job planning process
- To lead on developments in Breast Cancer genomics/genetics and tumour biology at Velindre Cancer Centre and contribute to horizon scanning and service development in this area.
- The post-holder will not be required to participate in the consultant acute oncology on-call rota but would review any team inpatients as necessary
- Provide virtual advice and to liaise with other health care providers, hospitals and primary care teams, as required
- To undertake the professional supervision and management of junior staff - in certain circumstances, the post-holder may be named as the clinical supervisor for junior staff
- To participate actively in clinical audit, in liaison with other colleagues and in line with the NHS Trust policy on the implementation of clinical governance
- To participate actively in Continuing Professional Development, in line with guidance from the Royal College of Physicians and in agreement with the Chief Executive of the relevant NHS Trust(s)
Other
- To engage effectively with industrial, commercial, and public sector organisations, charities, professional institutions, and other academic institutions, regionally and nationally to raise awareness of Cardiff Universitys and AWMGSs profile, to cultivate strategically valuable alliances, and to pursue opportunities for collaboration across a range of activities - these activities are expected to contribute to AWMGS and the enhancement of its regional and national profile
- To undergo personal and professional development that is appropriate to, and which will enhance performance
- To support and promote the Genomic Research Strategy in Wales, Wales Cancer Research Strategy and the Cardiff University Strategy
- To engage with Genomic Partnership Wales and its stakeholders, including patient and public representatives and patients to develop and promote genomic research - the role will specifically require engagement with clinicians from cancer centres across Wales, Centre for Trials Research and scientists within Cardiff University
- To participate in School of Medicine administration and activities to promote the School and its work to the wider University and the outside world
- Any other duties not included above, but consistent with the role
The post holder will also be expected to:
- Maintain scientific competency by attending relevant lectures, courses, seminars and conferences
- Contribute to the effective management of the Division, School and Research Theme at College, within the University
- Provide leadership that ensures Tripartite Collaboration between Cardiff and Vale; Cardiff University and Velindre
- Ensure compliance with legal and regulatory requirements in respect of equality and diversity, data protection, copyright and licensing, security, financial and other University policies, procedures and codes as appropriate
- Perform other academic duties, on an occasional basis, and by agreement, which are not included above, but which are consistent with the role
The post holder will be required to actively participate in, and comply fully with, the clinical academic/NHS Joint Appraisal Process and the requirements for consultant revalidation. The required arrangements are in place, as laid down by the Royal College of Physicians, to ensure that all doctors have an annual appraisal with a trained appraiser and supports clinical academic staff going through the revalidation process. Cardiff and Vale UHB will be the host organisation for revalidation.
A job plan will be agreed at appointment, please see provisional job plan in the full job description in supporting documents.
Person Specification
Qualifications
Essential
- Full General Medical Council registration and Licence to practise and Membership/Fellowship of the Royal College of Physicians (UK), or equivalent
- Certificate of Completion of Training (CCT), or equivalent and registration on the Specialist Register for Clinical Oncology/Clinical Genetics (or be within 6 months of eligibility for inclusion)
- Postgraduate research degree, PhD or equivalent, relevant to the research area outlined in the job description
Experience
Essential
- Significant experience of the management of breast cancer patients
- Significant experience of the diagnosis and management of patients with genetic diseases
- Ability to lead and direct a high-profile research programme and experience in supervising academic and clinical staff and of research team leadership
- Proven ability to attract independent, peer-reviewed research grant funding and proven track record of high-impact publications commensurate with the aims of the Division, School and University
- Significant experience of clinical trials and their governance and an understanding with evidence of the importance of the clinical impact of health research
- Experience of medical undergraduate and postgraduate teaching and supervision and clear evidence of commitment to nurture and support the development of the next generation of cancer research leaders
- Proven communication and networking skills, evidence of successful relationship building, initiative, and excellent project management abilities
Desirable
- Research interest congruent with existing research strengths in genetic and genomic medicine within the Division and experience of the mainstreaming of genomics into oncology
- Leadership experience in clinical research and/or associated translational research
- Evidence of vision and previous strategic leadership including the ability to lead on the integration of partnerships between NHS, Cardiff University and/or Industry
Other Criteria
Desirable
- Interest in paediatric cancer genetics
Person Specification
Qualifications
Essential
- Full General Medical Council registration and Licence to practise and Membership/Fellowship of the Royal College of Physicians (UK), or equivalent
- Certificate of Completion of Training (CCT), or equivalent and registration on the Specialist Register for Clinical Oncology/Clinical Genetics (or be within 6 months of eligibility for inclusion)
- Postgraduate research degree, PhD or equivalent, relevant to the research area outlined in the job description
Experience
Essential
- Significant experience of the management of breast cancer patients
- Significant experience of the diagnosis and management of patients with genetic diseases
- Ability to lead and direct a high-profile research programme and experience in supervising academic and clinical staff and of research team leadership
- Proven ability to attract independent, peer-reviewed research grant funding and proven track record of high-impact publications commensurate with the aims of the Division, School and University
- Significant experience of clinical trials and their governance and an understanding with evidence of the importance of the clinical impact of health research
- Experience of medical undergraduate and postgraduate teaching and supervision and clear evidence of commitment to nurture and support the development of the next generation of cancer research leaders
- Proven communication and networking skills, evidence of successful relationship building, initiative, and excellent project management abilities
Desirable
- Research interest congruent with existing research strengths in genetic and genomic medicine within the Division and experience of the mainstreaming of genomics into oncology
- Leadership experience in clinical research and/or associated translational research
- Evidence of vision and previous strategic leadership including the ability to lead on the integration of partnerships between NHS, Cardiff University and/or Industry
Other Criteria
Desirable
- Interest in paediatric cancer genetics
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
