Senior Development Scientist

Job summary

The Protein Development and Production Unit (PDPU) performs a vital role within NHS Blood and Transplant (NHSBT). PDPU was formed as part of the International Blood Group Reference Laboratory (IBGRL) in 1946 to centralise production of blood grouping reagents and provide a reference centre for the newly formed National Blood Service and is known internationally as a centre for excellence. The modern IBGRL Research Products produced by PDPU since 1991, have built up, year on year, a satisfied worldwide customer base. The PDPU is involved in a range of projects to develop and produce recombinant proteins and monoclonal antibodies. These reagents, some of which are CE marked, are used in diagnostic tests and for research. These reagents are supplied internally for use within NHSBT (e.g., to the Red Cell Immunohaematology (RCI) department which provides a role in solving complex serological cross matching cases in blood transfusion), and externally to hospitals, academic institutions, and commercial customers worldwide.

Main duties of the job

In this role you will be required to undertake routine and development activities within the Protein Development and Production Unit (PDPU) including production, Quality Control (QC) and development projects. You should have extensive experience in a wide range of laboratory techniques such as molecular biology, cell culture, immunoassay and protein purification. Other laboratory experience such as flow cytometry and serological testing would also be desirable. Your responsibilities will include: Performing highly specialist development activities in particular area(s) such as the development of soluble recombinant proteins as novel reagents for use within NHSBT (e.g. Red Cell Immunohaematology) using molecular and cellular techniques and the development of antibodies using a range of techniques. Production of soluble recombinant proteins and monoclonal antibodies to be used as research, diagnostic or CE marked reagents required by NHSBT and external customers & collaborators worldwide. The ability to prioritise workload against conflicting demands and be able to resolve a range of complex scientific/technical problems.

About us

At NHS Blood and Transplant, were incredibly proud of the many talented people who come together every day to make our organisation the very best it can be. We have clearly defined values that are centred around offering exceptional care to our donors and their families. We take care of each other too and we focus on building our expertise so we can change lives, provide quality support and offer fulfilling careers. Its an opportunity to contribute to a unique team as part of a service that saves lives 365 days a year. We offer brilliant benefits including 27 days of holiday (plus bank holidays), a comprehensive induction and training programme, and competitive pension scheme. We are passionate about creating an inclusive workplace and aim to reflect the diverse communities we work with and positively encourage applications from all sectors of the community. Three small words, one big difference - Caring, Expert and Quality. Together we'll save and improve more lives than ever