Band 6 Vector GMP Production Scientist

Job summary

A GMP scientist position is available within the Centre for Cell, Gene & Tissue Therapeutics. The post holder will be responsible for supporting a new, GMP-compliant lentiviral manufacturing facility in brand new, purpose-built clean rooms and assisting the development and implementation of novel intermediate scale lentiviral manufacturing techniques in suspension cell bioreactors.

The Post Holder will be responsible for GMP manufacture of lentiviral vector, and supporting the process development team transfer the process to GMP.

The post holder will also help to develop new downstream purification and packaging systems for the delivery of GMP-compliant lentiviral vectors to the cell manufacturing teams in the CCGTT.

Main duties of the job

The post requires exceptional attention to detail and the ability to work in a systematic manner whilst keeping detailed records. Perform QC testing on viral vectors: including flow cytometry, sterility testing and enumeration of viral preps and collating complex batch data for analysis and to interpret for final reporting. Calibration and maintenance of equipment for production and testing is required to maintain the laboratory.

Technical expertise in the in vitro culture of adherent and suspension cells and the ability to communicate ideas and practical skills to co-workers both at the bench and in formal presentations.

The post holder will be responsible to the Director of Vector for ensuring that the vector production laboratory is compliant with current legislation and best practice and will participate in the statutory regulatory inspections by MHRA.

About us

The Royal Free London NHS Foundation Trust is one of the UK's biggest and most innovative trusts. Across three main hospitals, our dedicated army of staff care for over 1.6million patients, treat more than 200,000 in A&E, deliver over 8,000 babies and carry out more than 17million tests.

Our size, scale and influence offer you unrivalled career opportunities and a forward-thinking approach to working that works around your lifestyle. From flexible hours and generous benefits, to next level training, we make it easier to take your career to the top.