Job summary
Duties and Responsibilities
Applications are invited for a Clinical Research Fellow position. You will be based at the UCL Movement Disorders Centre, spanning UCL and the Royal Free and UCLH sites. You will develop and execute a research project in Parkinson's disease and movement disorders genetics, under the supervision of Prof Huw Morris. The project will be based in part at the Department of Clinical and Movement Neuroscience, UCL. The project will include training in neurogenetics, gene / variant discovery and validation and in clinical trials based on genetic targets - focussed on Mendelian (single gene) disorders. The successful applicant will be expected to register for a PHD in a clinically based research project. The applicant will attend specialist clinics in movement disorders, paediatric movement disorders and neurogenetics and develop a lab based program of research. Further research aspects of the study may include development of cell models and the development of clinical trials related to genetic targets. This project will involve the analysis of large datasets through the GP2 project (https://gp2.org) based on large clinical cohorts established in the UK.
Key Requirements
Applicants should have be medically qualified and intend to pursue a career in Neurology and have a keen interest in Neurogenetics / Clinical Neuroscience. Experience in research and data analysis is desirable.
Main duties of the job
JOB SUMMARY: As a Clinical Research Fellow will be based at the UCL Movement Disorders Centre, spanning the Royal Free and UCLH sites. You will develop and execute a research project in Parkinson's disease and movement disorders genetics, under the supervision of Prof Huw Morris. The project will be based in part at the Department of Clinical and Movement Neuroscience, UCL. The project will include training in neurogenetics, gene / variant discovery and validation and in clinical trials based on genetic targets - focussed on Mendelian (single gene) disorders. The successful applicant will be expected to register for a PHD in a clinically based research project. The applicant will attend specialist clinics in movement disorders, paediatric movement disorders and neurogenetics and develop a lab based program of research. Further research aspects of the study may include development of cell models and the development of clinical trials related to genetic targets. This project will involve the analysis of large datasets through the GP2 project (https://gp2.org) based on large clinical cohorts established in the UK.
About us
Royal Free London NHS Foundation Trust
The Royal Free London NHS Foundation Trust runs three hospitals in London: Barnet Hospital, Chase Farm Hospital Royal Free Hospital
Across our three London hospitals, our vision is clear: to deliver world class expertise and local care.
We combine globally recognized clinical expertise with local and friendly hospital care to represent the NHS at its best.
Our mission is to be world class in terms of healthcare treatment, clinical research and teaching excellence. We aim to deliver and develop leading local healthcare in all three of our hospitals, to improve lives and help people thrive.
How the Royal Free will achieve its mission:
We will achieve our mission by making sure that we have:
- Excellent outcomes, in our clinical treatment, research and teaching
- Excellent experiences for patients, staff and GPs
- Excellent value, by improving the efficiency and productivity of our services, and reducing costs.
- Full compliance, meeting or exceeding all regulatory standards and outcomes we are set
- A strong organisation, investing effectively in our staff and infrastructure to make sure we are fit for future challenges
How the Royal Free measures its performance
In order to meet our aims, we want to ensure that our three London hospitals are in the top 10% of all healthcare providers for:
- quality of clinics and treatments
- medical research
- teaching and training new medical staff
- patient satisfaction and experience
- value for money
Job description
Job responsibilities
MAIN DUTIES AND RESPONSIBILITIES:
Duties of the Clinical Research Fellow post holder
The main duties of the post holder are to develop a research project related to the improved understanding and treatment of Parkinsons disease and related conditions through neurogenetics.
This research fellowship was set up based on a bequest from Dr Janet Owens, a Royal Free alumnus.
The primary role of the appointee will be
Investigation of the genetic basis of Parkinsons disease and related Movement Disorders
In addition
- Carry out clinical study assessments
- Prepare reports of study progress
- Deliver poster and oral presentations at National and International meetings
- Carry out and publish systematic reviews relating to aspects of Parkinsons and movement disorders genetics
- Develop clinical skills in movement disorders, taking advantage of the teaching and learning opportunities at the UCL Movement Disorders Centre
- Develop one or more research projects depending on the interests and skills of the successful applicant
- Across the centre, we can support further research based on: clinical trial, disease biomarkers, cell models, pharmacogenomics.
Development opportunities
There are extensive opportunities for personal development in the Neurology departments of the Royal Free Hospital, National Hospital for Neurology and UCL Movement Disorders Centre. It is anticipated that the successful candidate would either already hold a National Training Number in Neurology or apply for an NTN in the final year of their appointment.
This job description outlines the current main responsibilities of the post. However the duties of the post may change and develop over time and may therefore be amended in consultation with the post holder,
Job description
Job responsibilities
MAIN DUTIES AND RESPONSIBILITIES:
Duties of the Clinical Research Fellow post holder
The main duties of the post holder are to develop a research project related to the improved understanding and treatment of Parkinsons disease and related conditions through neurogenetics.
This research fellowship was set up based on a bequest from Dr Janet Owens, a Royal Free alumnus.
The primary role of the appointee will be
Investigation of the genetic basis of Parkinsons disease and related Movement Disorders
In addition
- Carry out clinical study assessments
- Prepare reports of study progress
- Deliver poster and oral presentations at National and International meetings
- Carry out and publish systematic reviews relating to aspects of Parkinsons and movement disorders genetics
- Develop clinical skills in movement disorders, taking advantage of the teaching and learning opportunities at the UCL Movement Disorders Centre
- Develop one or more research projects depending on the interests and skills of the successful applicant
- Across the centre, we can support further research based on: clinical trial, disease biomarkers, cell models, pharmacogenomics.
Development opportunities
There are extensive opportunities for personal development in the Neurology departments of the Royal Free Hospital, National Hospital for Neurology and UCL Movement Disorders Centre. It is anticipated that the successful candidate would either already hold a National Training Number in Neurology or apply for an NTN in the final year of their appointment.
This job description outlines the current main responsibilities of the post. However the duties of the post may change and develop over time and may therefore be amended in consultation with the post holder,
Person Specification
Values
Essential
- Demonstrable ability to meet the Trust Values
Education & professional Qualifications
Essential
- MBBS or equivalent
- Full current GMC registration
- MRCP Part 1
Desirable
- MRCP Part 2
- GCP research qualification
Experience
Essential
- Post qualification experience in Neurology
Desirable
- Experience in clinical and /or basic science research
- Experience in data analysis
Skills and aptitudes
Essential
- Good clinical skills
- Methodical approach to gathering and documenting data
- IT skills: e.g. database design and management,, MS Word, Excel
Desirable
- Data analysis skills: e.g. statistics, use of REDCAP, R and/or STATA
Personal Qualities & attributes
Essential
- Excellent organisational skills
- Interest in the neurogenetics of movement disorders/ neurodegenerative disease/ Parkinson's disease
Person Specification
Values
Essential
- Demonstrable ability to meet the Trust Values
Education & professional Qualifications
Essential
- MBBS or equivalent
- Full current GMC registration
- MRCP Part 1
Desirable
- MRCP Part 2
- GCP research qualification
Experience
Essential
- Post qualification experience in Neurology
Desirable
- Experience in clinical and /or basic science research
- Experience in data analysis
Skills and aptitudes
Essential
- Good clinical skills
- Methodical approach to gathering and documenting data
- IT skills: e.g. database design and management,, MS Word, Excel
Desirable
- Data analysis skills: e.g. statistics, use of REDCAP, R and/or STATA
Personal Qualities & attributes
Essential
- Excellent organisational skills
- Interest in the neurogenetics of movement disorders/ neurodegenerative disease/ Parkinson's disease
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
