Clinical research fellow in early phase cancer clinical trials

Oxford University NHS Foundation Trust

Information:

This job is now closed

Job summary

The Department of Oncology has an opportunity for a Clinical Research Fellow to work on the Early Phase Cancer Trials Unit at the University of Oxford from August 2022 (start date can be negotiated). The post holder will be working alongside staff in the Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and the University of Oxford. As part of the training programme the applicant will have the opportunity to undertake a clinical or translational research project at the Oxford Cancer Centre.

The Early Phase Cancer Trials Unit at the University of Oxford is a specialist, dedicated clinical trials unit, supporting early phase research integrating oncology and haematology as a seamless service. Recruiting 200 patients per year, our key remit is the testing of novel therapies, on a bespoke 15 bedded ward incorporating a sample handling laboratory. Under the direction of our Principle Investigators, who are world-leading clinicians and clinician scientists, a team of research nurses and clinical fellows work across the broad portfolio of studies, providing expertise in patient management and protocol compliance.

The successful candidate will be a GMC registered Medical Practitioner (or eligible for GMC registration), with relevant /substantial hospital service, including experience of managing cancer patients, and to have held specialist training hospital appointments in oncology or surgery.

Main duties of the job

The following responsibilities will be shared with other Clinical Research Fellows on the Unit.

Clinical and Research Responsibilities:

Inpatient and outpatient care of cancer patients being treated as part of trials performed on the EPCTU;

Co-ordination and execution of trial activities for EPCTU, including (but not limited to) study specific investigations, sample collection and handling, data collection, case record folder completion, maintenance of study documentation;

Under supervision, to undertake the setting up of clinical trials, including protocol design, grant applications, regulatory and ethical submissions, liaison with clinical trials units and preparation of study specific documentation.

Preparation of manuscripts for publication.

About us

Oxford University Hospitals NHS Foundation Trust is one of the largest NHS teaching trusts in the country. It provides a wide range of general and specialist clinical services and is a base for medical education, training and research. Find out more here www.ouh.nhs.uk

The Trust comprises four hospitals - the John Radcliffe Hospital, Churchill Hospital and Nuffield Orthopaedic Centre in Headington and the Horton General Hospital in Banbury.

Our values, standards and behaviours define the quality of clinical care we offer and the professional relationships we make with our patients, colleagues and the wider community. We call thisDelivering Compassionate Excellenceand its focus is on our values of compassion, respect, learning, delivery, improvement and excellence. These values put patients at the heart of what we do and underpin the quality healthcare we would like for ourselves or a member of our family. Watch how we set out to deliver compassionate excellence via theOUH YouTube channel.

Date posted

16 June 2022

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£51,017 a year per annum

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

321-S6-1439-JA-B

Job locations

Churchill Hospital

Oxford

OX3 7LJ


Job description

Job responsibilities

1. JOB TITLE: Full time Clinical Research Fellow in Oncology

2. GRADE: Specialist Registrar

3. DEPARTMENT: Oncology

4. ACCOUNTABLE TO: Director, Early Phase Cancer Trials Unit

5. PRINCIPAL ACTIVITIES:

The following responsibilities will be shared with other Clinical Research Fellows on the Unit.

Clinical and Research Responsibilities:Inpatient and outpatient care of cancer patients being treated as part of trials performed on the EPCTU;

Co-ordination and execution of trial activities for EPCTU, including (but not limited to) study specific investigations, sample collection and handling, data collection, case record folder completion, maintenance of study documentation;

Under supervision, to undertake the setting up of clinical trials, including protocol design, grant applications, regulatory and ethical submissions, liaison with clinical trials units and preparation of study specific documentation.

Preparation of results for publication.

The post holder's duties will be primarily at the Churchill Hospital but their presence may from time to time be required in other parts of the Trust.

Weekly Timetable: Monday am EPCTU pm Phase 1 Clinic

Tuesday am EPCTUpm Data management

Wednesday am EPCTUpm Data management

Thursday am EPCTU pm EPCTU / Project specific study

Friday am EPCTUpm MDT / Data management

The sessions timetabled are flexible, as the work involved in supporting trials is varied. The nature of the clinical trials work will change according to the status of each protocol and the number of patients on trial at any given time.

Note: The above description is a guide and should not be regarded as definitive or restrictive and may be changed.

Education and Training:The post-holder will join with post-graduate fellowship programmes operating within the Departments of Oncology and the NIHR Biomedical Research Centre.

Teaching, Audit and Research:Participate in teaching of the specialist registrars and occasionally other medical and non-medical personnel. Participation in audit will be required, with an emphasis on research governance.

Administrative responsibilities:Undertake the administrative work associated with the duties outlined above. Administrative support will be provided by the Early Phase Trials Research Hub.

General responsibilities:Act at all times in the interests of the Department, Oxford NIHR Biomedical Research Centre, and the OUH Trust to ensure good practice.

Be accountable for your own professional conduct at all times.

Ensure that work is conducted safely and, in particular, persons undertaking the work do so according to policies and appropriate safety procedures in the dedicated areas. Undertake duties as may be required from time to time that are commensurate with the grade and responsibilities of the post.

So far as is consistent with the proper discharge of the above duties the post-holder will be expected to deputize from time to time for absent colleagues.

Perform additional duties in occasional emergencies and unforeseen circumstances.

To be available for such irregular commitments outside normally rostered duties as are essential for continuity of patient care.

The post-holder will be required to work within the Trust's management policies and procedures, both statutory and internal.

Please note:

No on call commitment is included with this post, but could be available by negotiation.

The post holder is not required to be resident in the hospital.

ONCOLOGY AND HAEMATOLOGY DIRECTORATE

The Directorate comprises of 4 departments: Clinical Haematology (including Thrombosis and Haemophilia), Oncology (incorporating Clinical and Medical Oncology), Palliative Care and Medical Physics.

The Lead Clinicians are:

Haematology: Dr Sandy Hayes

Oncology: Dr Miranda Payne

Palliative Care: Professor Bee Wee

Medical Physics: Professor Malcolm Sperrin

The Department registered around 6,000 new referrals during 2018-19, and provides patients with comprehensive care to include full assessment and treatment with both radiotherapy (3400 new patients, 52000 fractions) and chemotherapy (11,000 day unit attendances in OUH and Horton). In addition, a significant outpatient and chemotherapy workload is undertaken by our consultants visiting surrounding DGHs.

There are 54 consultant oncologist posts. There are 19 Medical Oncologists (of whom 8 are in university posts). There is close integration between the NHS Department of Oncology (Clinical Director, Prof Bass Hassan) and the University of Oxford Department of Oncology (Head Prof Mark Middleton). All consultants (NHS and University, Clinical and Medical Oncology) have shared offices and secretarial support in the Cancer Centre; grouped together in tumour site pods.

In March 2009 we moved into the new Oxford Cancer Centre on the Churchill site. This £110 million project saw the relocation of services for both surgical and non-surgical oncology and haematology into the new build.

For oncology there is an integrated ward of 26 beds for acute admissions (18), overnight chemotherapy admissions (4) along with 4 designated radiation protection beds. There is a linked 5 bed triage area, and 15 bed day case research area and laboratories to support the research. The nurse led triage service currently runs 7 days a week, 10 hours per day. There is a combined haematology and oncology outpatient area and chemotherapy suite.

A variety of combined clinics are held at The Churchill and the John Radcliffe Hospitals including combined or parallel clinics for the management of lung, breast, haematological, endocrine, dermatological, gynaecological and head and neck cancers, upper GI cancer amongst others

The Maggies Cancer Information Centre is in new accommodation that opened in 2014, and is adjacent to the cancer centre. The presence of the Maggies facility on site allows the provision of a more holistic approach to care which the department has expanded on through a cancer specific psychological medicine service.

The new Gray Institute for Radiation Oncology and Physics opened on the Churchill site in 2008. The University of Oxford, Department of Oncology was formed in 2011, which brings together world-leading research teams in cancer.

Candidates are invited to contact Dr Simon Lord (simon.lord@oncology.ox.ac.uk) Consultant Medical Oncologist, (Tel: Oxford (01865) 235315) in the first instance for further details / informal visits.

Job description

Job responsibilities

1. JOB TITLE: Full time Clinical Research Fellow in Oncology

2. GRADE: Specialist Registrar

3. DEPARTMENT: Oncology

4. ACCOUNTABLE TO: Director, Early Phase Cancer Trials Unit

5. PRINCIPAL ACTIVITIES:

The following responsibilities will be shared with other Clinical Research Fellows on the Unit.

Clinical and Research Responsibilities:Inpatient and outpatient care of cancer patients being treated as part of trials performed on the EPCTU;

Co-ordination and execution of trial activities for EPCTU, including (but not limited to) study specific investigations, sample collection and handling, data collection, case record folder completion, maintenance of study documentation;

Under supervision, to undertake the setting up of clinical trials, including protocol design, grant applications, regulatory and ethical submissions, liaison with clinical trials units and preparation of study specific documentation.

Preparation of results for publication.

The post holder's duties will be primarily at the Churchill Hospital but their presence may from time to time be required in other parts of the Trust.

Weekly Timetable: Monday am EPCTU pm Phase 1 Clinic

Tuesday am EPCTUpm Data management

Wednesday am EPCTUpm Data management

Thursday am EPCTU pm EPCTU / Project specific study

Friday am EPCTUpm MDT / Data management

The sessions timetabled are flexible, as the work involved in supporting trials is varied. The nature of the clinical trials work will change according to the status of each protocol and the number of patients on trial at any given time.

Note: The above description is a guide and should not be regarded as definitive or restrictive and may be changed.

Education and Training:The post-holder will join with post-graduate fellowship programmes operating within the Departments of Oncology and the NIHR Biomedical Research Centre.

Teaching, Audit and Research:Participate in teaching of the specialist registrars and occasionally other medical and non-medical personnel. Participation in audit will be required, with an emphasis on research governance.

Administrative responsibilities:Undertake the administrative work associated with the duties outlined above. Administrative support will be provided by the Early Phase Trials Research Hub.

General responsibilities:Act at all times in the interests of the Department, Oxford NIHR Biomedical Research Centre, and the OUH Trust to ensure good practice.

Be accountable for your own professional conduct at all times.

Ensure that work is conducted safely and, in particular, persons undertaking the work do so according to policies and appropriate safety procedures in the dedicated areas. Undertake duties as may be required from time to time that are commensurate with the grade and responsibilities of the post.

So far as is consistent with the proper discharge of the above duties the post-holder will be expected to deputize from time to time for absent colleagues.

Perform additional duties in occasional emergencies and unforeseen circumstances.

To be available for such irregular commitments outside normally rostered duties as are essential for continuity of patient care.

The post-holder will be required to work within the Trust's management policies and procedures, both statutory and internal.

Please note:

No on call commitment is included with this post, but could be available by negotiation.

The post holder is not required to be resident in the hospital.

ONCOLOGY AND HAEMATOLOGY DIRECTORATE

The Directorate comprises of 4 departments: Clinical Haematology (including Thrombosis and Haemophilia), Oncology (incorporating Clinical and Medical Oncology), Palliative Care and Medical Physics.

The Lead Clinicians are:

Haematology: Dr Sandy Hayes

Oncology: Dr Miranda Payne

Palliative Care: Professor Bee Wee

Medical Physics: Professor Malcolm Sperrin

The Department registered around 6,000 new referrals during 2018-19, and provides patients with comprehensive care to include full assessment and treatment with both radiotherapy (3400 new patients, 52000 fractions) and chemotherapy (11,000 day unit attendances in OUH and Horton). In addition, a significant outpatient and chemotherapy workload is undertaken by our consultants visiting surrounding DGHs.

There are 54 consultant oncologist posts. There are 19 Medical Oncologists (of whom 8 are in university posts). There is close integration between the NHS Department of Oncology (Clinical Director, Prof Bass Hassan) and the University of Oxford Department of Oncology (Head Prof Mark Middleton). All consultants (NHS and University, Clinical and Medical Oncology) have shared offices and secretarial support in the Cancer Centre; grouped together in tumour site pods.

In March 2009 we moved into the new Oxford Cancer Centre on the Churchill site. This £110 million project saw the relocation of services for both surgical and non-surgical oncology and haematology into the new build.

For oncology there is an integrated ward of 26 beds for acute admissions (18), overnight chemotherapy admissions (4) along with 4 designated radiation protection beds. There is a linked 5 bed triage area, and 15 bed day case research area and laboratories to support the research. The nurse led triage service currently runs 7 days a week, 10 hours per day. There is a combined haematology and oncology outpatient area and chemotherapy suite.

A variety of combined clinics are held at The Churchill and the John Radcliffe Hospitals including combined or parallel clinics for the management of lung, breast, haematological, endocrine, dermatological, gynaecological and head and neck cancers, upper GI cancer amongst others

The Maggies Cancer Information Centre is in new accommodation that opened in 2014, and is adjacent to the cancer centre. The presence of the Maggies facility on site allows the provision of a more holistic approach to care which the department has expanded on through a cancer specific psychological medicine service.

The new Gray Institute for Radiation Oncology and Physics opened on the Churchill site in 2008. The University of Oxford, Department of Oncology was formed in 2011, which brings together world-leading research teams in cancer.

Candidates are invited to contact Dr Simon Lord (simon.lord@oncology.ox.ac.uk) Consultant Medical Oncologist, (Tel: Oxford (01865) 235315) in the first instance for further details / informal visits.

Person Specification

GMC Registration

Essential

  • Full, or eligibility for full registration and licence to practise

Qualifications/Training

Essential

  • MB ChB or equivalent. MRCP, or equivalent.

Desirable

  • A postgraduate qualification
  • Holder of a national training number in medical or clinical oncology, or equivalent.

Experience

Essential

  • General training in Oncology, three years full time hospital service, including direct experience of managing cancer patients.
  • Post-foundation hospital appointments in oncology and/or haematology.
  • Demonstrable ability to exercise an immediate level of clinical responsibility as delegated by the consultant-in-charge.

Desirable

  • Training at registrar level in Oncology

Skills and Knowledge

Essential

  • Ability to work effectively within a multi-professional team.
  • Excellent organisational, communication, professional and personal skills.
  • Good written English. Communication skills should be highly developed.
  • Experience of teaching undergraduates and trainees.
  • Evidence of effective participation in clinical audit and risk management
  • Evidence of active involvement in clinical research trials

Desirable

  • Training in research conduct, including ICH-GCP.
  • Computing skills: ability to use word processor, spreadsheet programme and web browser.
  • Publication of research
Person Specification

GMC Registration

Essential

  • Full, or eligibility for full registration and licence to practise

Qualifications/Training

Essential

  • MB ChB or equivalent. MRCP, or equivalent.

Desirable

  • A postgraduate qualification
  • Holder of a national training number in medical or clinical oncology, or equivalent.

Experience

Essential

  • General training in Oncology, three years full time hospital service, including direct experience of managing cancer patients.
  • Post-foundation hospital appointments in oncology and/or haematology.
  • Demonstrable ability to exercise an immediate level of clinical responsibility as delegated by the consultant-in-charge.

Desirable

  • Training at registrar level in Oncology

Skills and Knowledge

Essential

  • Ability to work effectively within a multi-professional team.
  • Excellent organisational, communication, professional and personal skills.
  • Good written English. Communication skills should be highly developed.
  • Experience of teaching undergraduates and trainees.
  • Evidence of effective participation in clinical audit and risk management
  • Evidence of active involvement in clinical research trials

Desirable

  • Training in research conduct, including ICH-GCP.
  • Computing skills: ability to use word processor, spreadsheet programme and web browser.
  • Publication of research

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Oxford University NHS Foundation Trust

Address

Churchill Hospital

Oxford

OX3 7LJ


Employer's website

https://www.ouh.nhs.uk/ (Opens in a new tab)

Employer details

Employer name

Oxford University NHS Foundation Trust

Address

Churchill Hospital

Oxford

OX3 7LJ


Employer's website

https://www.ouh.nhs.uk/ (Opens in a new tab)

For questions about the job, contact:

Consultant Medical Oncologist

Simon Lord

simon.lord@oncology.ox.ac.uk

01865235315

Date posted

16 June 2022

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£51,017 a year per annum

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

321-S6-1439-JA-B

Job locations

Churchill Hospital

Oxford

OX3 7LJ


Supporting documents

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