Job summary
Principal Research Bioinformatician
(Genomics)
An exciting opportunity has arisen in the West Midlands Regional Genetics
Laboratory (WMRGL) in Birmingham for a Principal Research Bioinformatician to
join our dynamic team of scientists & technologists. Applications are
invited from skilled, innovative and motivated Bioinformaticians with an
interest in human genetics.
This post will provide bioinformatic
leadership in the delivery of research projects within the WMRGL and those
developed and undertaken in collaboration with the Central & South (CAS) Genomic
Medicine Service Alliance (GMSA).
The WMRGL is the designated Genomic Laboratory
Hub leading the CAS GLH Consortium providing state of the art genomic analysis
to patients with rare disease/cancer. Research and development is fundamental
to the successful delivery of this high profile service.
The WMRGL is based at Birmingham Womens and
Childrens NHS FT, working closely with Clinical Genetics, mainstream
Clinicians, academia and pharmaceutical industries.
Main duties of the job
The successful candidate
will have a first degree in Computer Science/Health Informatics/Mathematics or
related discipline, have completed a higher degree with significant
bioinformatic content and experience of the application of bioinformatics in a
research setting. Knowledge of next generation sequencing, quality management,
web development and database management is essential. Flexible/remote working
will be considered.
You will provide
bioinformatics support for the delivery of research projects within the GLH and
GMSA, be responsible for the testing, validation and implementation of
analytical pipelines to analyse genomic data (including NGS & other
emerging genomic technologies).
Working closely with the
departmental Lead Bioinformaticians as well as the GLH Scientific Director and
Cancer and Rare Disease Scientific leads, and the GMSA Research Directors, you
will be required to provide advice on bioinformatics strategy as well as
networking with other bioinformatics groups within the GMSA, NHS, academia and
industry.
For further information about
the post please contact Yvonne Wallis y.wallis@nhs.net or Sarah Ennis S.Ennis@soton.ac.uk .
About us
Birmingham Women's and Children's NHS Foundation Trust is the
first of its type in the UK. Our Trust was formed in February 2017 to drive
forward our commitment to provide the highest quality, world-class physical and
mental health care for our women, children and families.
Uniting our hospitals means more seamless care; more investment
to make greater advances in our specialist treatment and world-leading
neo-natal and fetal work. Importantly, it also gives us a greater voice in
shaping the future of family-centred care.
Birmingham Children's Hospital is a UK leading specialist
paediatric centre with an international reputation in several areas. Birmingham
Women's Hospital is one of two dedicated women's hospitals in the UK, with the
busiest single site maternity unit, delivering more than 8,200 babies a year
offering a full range of gynaecological, maternity and neonatal care. Forward
Thinking Birmingham (FTB) Mental Health Services are a unique, innovative
community and inpatient mental health partnership. Alongside partners FTB
offers care pathways of mental health assessment and treatment for young people
aged 0-25 years old.
Our Trust is committed to creating the best place to work. We
believe in promoting and enhancing inclusion, diversity and equality and
encourage applications from all areas of the community, who meet the criteria
for the role, regardless of age, gender identity, disability, race, religion or
sexual orientation.
Job description
Job responsibilities
Please refer to the attached job description and person
specification to view the full details for this opportunity at Birmingham
Womens and Childrens NHS Foundation Trust.
When completing your application, please ensure you have
evidenced how you meet the job description and person specification to include
transferable experience, qualifications, skills along with professional
registration details (if applicable).
Occasionally we receive a large number of applications for
our roles and when that happens we sometimes bring the closing date forward, so
please apply promptly to avoid disappointment.
Job description
Job responsibilities
Please refer to the attached job description and person
specification to view the full details for this opportunity at Birmingham
Womens and Childrens NHS Foundation Trust.
When completing your application, please ensure you have
evidenced how you meet the job description and person specification to include
transferable experience, qualifications, skills along with professional
registration details (if applicable).
Occasionally we receive a large number of applications for
our roles and when that happens we sometimes bring the closing date forward, so
please apply promptly to avoid disappointment.
Person Specification
Qualifications
Essential
- Degree in Computer Science or a Health Informatics discipline (first or second class with Honours) in OR relevant Biological Science with demonstrable abilities in informatics or computing
- MSc in informatics/bioinformatics or equivalent
- Active participation in CPD
- Participation in departmental seminars/journal clubs
- Involvement in new developments for the department
Desirable
- Completed Training for Trainers
- Contribute to departmental publications
- PhD
- Certificate of Competence/MSC healthcare scientist training programme
- State Registration with the Health Professional Council
- Evidence of additional role(s) within the department
Experience
Essential
- Previous experience of bioinformatics and familiarity with NGS data pipelines including the use of automated pipeline tools such as the Ruffus framework. Proficiency in Python or Perl programming
- Administration and installation of Galaxy bioinformatic analysis environment
- Knowledge of virtual machines, including administration, snapshotting and deployment within a corporate IT environment
- Knowledge of Unix/Linux environment, experience with XML and JSON
- Experience of software/algorithm development, testing, introduction, maintenance and support
- Ability to evaluate new technologies and informatics tools relevant to a modern genetics laboratory
- Knowledge of database design, development and administration including evaluating and understanding database schemas (data models)
- Experience of project management
- Knowledge of principles of molecular biology and clinical laboratory genetics
- Knowledge of the principles of molecular genomics techniques and of basic molecular biology techniques
- Experience of software/web based tools for genetic data analysis and pathogenicity prediction tools (e.g. SIFT, PolyPhen)
- Knowledge of networking and the understanding of the infrastructure and hardware requirements to achieve this
- Knowledge of LIMS IT systems and appropriate automated software packages
Desirable
- Knowledge of Trust and laboratory polices, codes of practice and professional guidelines
- Containerisation of pipelines/ software
Person Specification
Qualifications
Essential
- Degree in Computer Science or a Health Informatics discipline (first or second class with Honours) in OR relevant Biological Science with demonstrable abilities in informatics or computing
- MSc in informatics/bioinformatics or equivalent
- Active participation in CPD
- Participation in departmental seminars/journal clubs
- Involvement in new developments for the department
Desirable
- Completed Training for Trainers
- Contribute to departmental publications
- PhD
- Certificate of Competence/MSC healthcare scientist training programme
- State Registration with the Health Professional Council
- Evidence of additional role(s) within the department
Experience
Essential
- Previous experience of bioinformatics and familiarity with NGS data pipelines including the use of automated pipeline tools such as the Ruffus framework. Proficiency in Python or Perl programming
- Administration and installation of Galaxy bioinformatic analysis environment
- Knowledge of virtual machines, including administration, snapshotting and deployment within a corporate IT environment
- Knowledge of Unix/Linux environment, experience with XML and JSON
- Experience of software/algorithm development, testing, introduction, maintenance and support
- Ability to evaluate new technologies and informatics tools relevant to a modern genetics laboratory
- Knowledge of database design, development and administration including evaluating and understanding database schemas (data models)
- Experience of project management
- Knowledge of principles of molecular biology and clinical laboratory genetics
- Knowledge of the principles of molecular genomics techniques and of basic molecular biology techniques
- Experience of software/web based tools for genetic data analysis and pathogenicity prediction tools (e.g. SIFT, PolyPhen)
- Knowledge of networking and the understanding of the infrastructure and hardware requirements to achieve this
- Knowledge of LIMS IT systems and appropriate automated software packages
Desirable
- Knowledge of Trust and laboratory polices, codes of practice and professional guidelines
- Containerisation of pipelines/ software
Additional information
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Employer details
Employer name
Birmingham Women's and Children's NHS Foundation Trust
Address
Birmingham Womens Hospital Nhs Trust
Mindelsohn Way
Birmingham
B15 2TG
Employer's website
https://bwc.nhs.uk/ (Opens in a new tab)
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