Job summary
An exciting
opportunity has arisen in the West Midlands Regional Genetics Laboratory
(WMRGL) in Birmingham for two Bioinformaticians to join our dynamic team of
scientists & technologists. Applications are invited from skilled and
motivated Bioinformaticians with an interest in human genetics. Flexible/remote
working will be considered.
Genomic testing has significantly expanded in recent years with the
introduction of large gene panels and exomes increasing the complexity of
analysis and reporting. These posts will support the delivery of two clinical
programmes and play a key role in future developments as part of the National
Genomics Medicine Service in England.
The WMRGL is the designated Genomic Laboratory Hub leading the Central
& South GLH Consortium providing state of the art genomic analysis to
patients with rare disease/cancer. Our workforce is fundamental to the
successful delivery of this high profile service.
The WMRGL is based at Birmingham Womens and Childrens NHS FT, working
closely with Clinical Genetics, the Genomic Medicine Service Alliance, the
National School of Healthcare Science, academia and pharmaceutical industries. We
are committed to training and developing our staff at all levels supporting
Continuing Professional Development.
Main duties of the job
The successful candidate will have a degree in Computer Science/Health Informatics discipline, be either HCPC registered or have equivalent experience & qualifications. Experience in next generation sequencing, quality management, web development and database management is essential.
You will provide
bioinformatics support for genetics services and research projects, be responsible for the testing,
validation and implementation of analytical pipelines to analyse genomic data
(including NGS, microarray & other emerging genomic technologies). A
priority will be to support our growing cancer genomics services as part of the
national guidance on cancer testing. Expertise is also required for rapid exome
analysis and distributed analysis solutions. You will play a
significant role in the development of bioinformatics validation tools to
assist the interpretation of genetic variants.
Working closely
with the departmental Lead Bioinformaticians you will be encouraged to provide
advice on bioinformatics strategy as well as networking with other
bioinformatics groups within the NHS, academia and industry.
BWC NHS FT is committed
to providing equality of opportunity in all aspects of employment, to every
member of staff and to all potential employees. The Trust aims to build a
workforce which is valued and whose diversity reflects the communities it
serves, enabling it to deliver the best possible healthcare service to those
communities.
About us
Birmingham Women's and Children's NHS Foundation Trust is the first of its type in the UK. Our Trust was formed in February 2017 to drive forward our commitment to provide the highest quality, world-class physical and mental health care for our women, children and families.
Uniting our hospitals means more seamless care; more investment to make greater advances in our specialist treatment and world-leading neo-natal and fetal work. Importantly, it also gives us a greater voice in shaping the future of family-centred care.
Birmingham Children's Hospital is a UK leading specialist paediatric centre with an international reputation in several areas. Birmingham Women's Hospital is one of two dedicated women's hospitals in the UK, with the busiest single site maternity unit, delivering more than 8,200 babies a year offering a full range of gynaecological, maternity and neonatal care. Forward Thinking Birmingham (FTB) Mental Health Services are a unique, innovative community and inpatient mental health partnership. Alongside partners FTB offers care pathways of mental health assessment and treatment for young people aged 0-25 years old.
Our Trust is
committed to creating the best place to work. We believe in promoting and
enhancing inclusion, diversity and equality and encourage applications from all
areas of the community, who meet the criteria for the role, regardless of age,
gender identity, disability, race, religion or sexual orientation.
Job description
Job responsibilities
Please refer to the
attached job description and person specification to view the full details for
this opportunity at Birmingham Womens and Childrens NHS Foundation Trust.
When completing
your application, please ensure you have evidenced how you meet the job description
and person specification to include transferable experience, qualifications,
skills along with professional registration details (if applicable).
Occasionally we
receive a large number of applications for our roles and when that happens we
sometimes bring the closing date forward, so please apply promptly to avoid
disappointment.
Job description
Job responsibilities
Please refer to the
attached job description and person specification to view the full details for
this opportunity at Birmingham Womens and Childrens NHS Foundation Trust.
When completing
your application, please ensure you have evidenced how you meet the job description
and person specification to include transferable experience, qualifications,
skills along with professional registration details (if applicable).
Occasionally we
receive a large number of applications for our roles and when that happens we
sometimes bring the closing date forward, so please apply promptly to avoid
disappointment.
Person Specification
Analytical and Judgement Skills
Essential
- Excellent problem-solving skills and ability to adapt to new problems and ideas.
Qualifications
Essential
- Degree in Computer Science or a Health Informatics discipline (first or second class with Honours) in OR relevant Biological
- Science with demonstrable abilities in informatics or computing
- MSc in informatics/bioinformatics or equivalent
- Active participation in CPD
- Participation in departmental seminars/journal clubs
Desirable
- State Registration as a Clinical Scientist with the Health Professional Council
- Certificate of Competence/MSC healthcare scientist training programme
- Contribute to publications
- Completed Training for Trainers
Professional / Managerial / Specialist Knowledge
Essential
- Ability to communicate highly complex information in both verbal and written formats.
- Proven organisational skills.
- Excellent organisational skills.
- Ability to work independently under the direction of senior staff.
- Ability to pay attention to detail and maintain accurate records.
- Effective team worker and ability to give technical training to other staff.
- Ability to produce bioinformatics pipelines to acceptable standards of quality and accuracy for NGS data and other genomic technologies.
- Ability to communicate scientific and bioinformatic findings to local and national meetings and conferences.
Experience
Essential
- Previous experience of bioinformatics and familiarity with NGS pipelines including analysis of genomic sequence data using appropriate bioinformatic software.
- Involvement in new developments.
- Knowledge of Linux and commonly used command line tools
- Ability to evaluate new technologies and informatics tools relevant to a modern genetics laboratory.
- Experience of software/algorithm development, testing, introduction, maintenance and support.
- Knowledge of database design, development and administration including evaluating and understanding database schemas (data models).
- Knowledge of principles of molecular biology and clinical laboratory genetics.
- Knowledge of the principles of molecular genomics techniques and of basic molecular biology techniques.
- Experience of software/web based tools for genetic data analysis and pathogenicity prediction tools (e.g. SIFT, PolyPhen).
- Knowledge of LIMS IT systems and appropriate automated software packages.
Desirable
- Previous experience of web development.
- Evidence of additional role(s).
- Working knowledge of Django framework.
- Experience of project management.
- Knowledge of Trust and laboratory polices codes of practice and professional guidelines.
Personal Skills / Abilities and Attributes
Essential
- Ability to work under pressure.
- Flexible approach to work to tight deadlines.
- Good interpersonal skills to enable adequate communication with a wide range of clinical and non-clinical colleagues as well as academic and other IT professionals.
- Enthusiasm/motivation.
- Self-motivated and desire to develop new skills as required.
Desirable
Person Specification
Analytical and Judgement Skills
Essential
- Excellent problem-solving skills and ability to adapt to new problems and ideas.
Qualifications
Essential
- Degree in Computer Science or a Health Informatics discipline (first or second class with Honours) in OR relevant Biological
- Science with demonstrable abilities in informatics or computing
- MSc in informatics/bioinformatics or equivalent
- Active participation in CPD
- Participation in departmental seminars/journal clubs
Desirable
- State Registration as a Clinical Scientist with the Health Professional Council
- Certificate of Competence/MSC healthcare scientist training programme
- Contribute to publications
- Completed Training for Trainers
Professional / Managerial / Specialist Knowledge
Essential
- Ability to communicate highly complex information in both verbal and written formats.
- Proven organisational skills.
- Excellent organisational skills.
- Ability to work independently under the direction of senior staff.
- Ability to pay attention to detail and maintain accurate records.
- Effective team worker and ability to give technical training to other staff.
- Ability to produce bioinformatics pipelines to acceptable standards of quality and accuracy for NGS data and other genomic technologies.
- Ability to communicate scientific and bioinformatic findings to local and national meetings and conferences.
Experience
Essential
- Previous experience of bioinformatics and familiarity with NGS pipelines including analysis of genomic sequence data using appropriate bioinformatic software.
- Involvement in new developments.
- Knowledge of Linux and commonly used command line tools
- Ability to evaluate new technologies and informatics tools relevant to a modern genetics laboratory.
- Experience of software/algorithm development, testing, introduction, maintenance and support.
- Knowledge of database design, development and administration including evaluating and understanding database schemas (data models).
- Knowledge of principles of molecular biology and clinical laboratory genetics.
- Knowledge of the principles of molecular genomics techniques and of basic molecular biology techniques.
- Experience of software/web based tools for genetic data analysis and pathogenicity prediction tools (e.g. SIFT, PolyPhen).
- Knowledge of LIMS IT systems and appropriate automated software packages.
Desirable
- Previous experience of web development.
- Evidence of additional role(s).
- Working knowledge of Django framework.
- Experience of project management.
- Knowledge of Trust and laboratory polices codes of practice and professional guidelines.
Personal Skills / Abilities and Attributes
Essential
- Ability to work under pressure.
- Flexible approach to work to tight deadlines.
- Good interpersonal skills to enable adequate communication with a wide range of clinical and non-clinical colleagues as well as academic and other IT professionals.
- Enthusiasm/motivation.
- Self-motivated and desire to develop new skills as required.
Desirable
Additional information
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
Employer details
Employer name
Birmingham Women's and Children's NHS Foundation Trust
Address
Birmingham Womens Hospital Nhs Trust
Mindelsohn Way
Birmingham
B15 2TG
Employer's website
https://bwc.nhs.uk/ (Opens in a new tab)
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