Job summary
We are seeking a skilled and enthusiastic clinical bioinformatician to join our team based in the North Thames Genomic Laboratory Hub at Great Ormond Street Hospital. Our team is delivering transformation in patient care by developing new pipelines for rapid, comprehensive diagnosis of paediatric conditions to transform clinical services.
If you are committed to contributing to a team delivering excellence in research in genetics and genomics and would like to gain experience in clinical bioinformatics this is definitely the post for you. This Band 7 post is available immediately for one year. You will be joining an enthusiastic, friendly, motivated clinical bioinformatics team. This is an ideal opportunity to seriously contribute to translating research into clinical practice for the benefit of patients. This post is suitable for registered clinical bioinformaticians or trainee bioinformaticians close to registration.
Main duties of the job
- To provide high end bioinformatics knowledge and support in the delivery of a reliable, competitive, efficient, cost effective and high-quality research and development programme that ultimately contributes to the diagnostic service
- To pro-actively propose and develop improvements to the clinical service
- To work with the Clinical Bioinformatics team along with other GLHs as required to facilitate the translation of research to clinical service.
- To develop collaborative projects with fellow professionals from across the GLH and other national and international institutions as appropriate
- To develop novel approaches to CNV analysis
About us
GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.
We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.
We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.
We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.
We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment.
Person Specification
GOSH Culture and Values
Essential
- Our Always values
- Able to work on site when required
Academic/Professional qualification/Training
Essential
- State Registered Clinical Bioinformatician (HCPC)
- MSc in Bioinformatics/Computational Biology or equivalent Postgraduate qualification
Desirable
- Higher degree (PhD) in Bioinformatics or a related field
Experience/Knowledge
Essential
- Knowledge of python programming
- Knowledge of confidentiality and data protection processes and procedures
- Experience of developing, implementing and maintaining bioinformatic data analysis pipelines
- Experience with creating, querying and maintaining databases, particularly MySQL or PostgreSQL
- Advanced use of git version control
- Demonstrable experience in a clinical diagnostic department
- Experience in deploying production ready applications to support genetic diagnostic services
- Knowledge of bash and shell scripting
- Ability to work in a Unix/Linux environment
- Detailed knowledge of core computer service concepts
- Up to date knowledge of the relevant scientific literature
- Evidence of professional and personal development.
Desirable
- Experience usAdvanced knowledge of the Python programming language, and commonly used Python libraries and web frameworks (e.g. Django and Flask)ing docker for development
- Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)
- Experience testing python code e.g. using pytest
Skills/Abilities
Essential
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Ability to develop and maintain excellent communication and working relationships
- Advanced problem-solving skills
- Able to provide specialist advice to laboratory staff
- Able to present data at departmental and inter-departmental meetings
- Awareness of clinical significance of genetics findings and implications for patients
- Work to deadlines, operating autonomously and as part of a team
- Knowledge and understanding of ISO15189 accreditation standards and their application to a genomics laboratory
- Ability to write and follow bioinformatics protocols
Person Specification
GOSH Culture and Values
Essential
- Our Always values
- Able to work on site when required
Academic/Professional qualification/Training
Essential
- State Registered Clinical Bioinformatician (HCPC)
- MSc in Bioinformatics/Computational Biology or equivalent Postgraduate qualification
Desirable
- Higher degree (PhD) in Bioinformatics or a related field
Experience/Knowledge
Essential
- Knowledge of python programming
- Knowledge of confidentiality and data protection processes and procedures
- Experience of developing, implementing and maintaining bioinformatic data analysis pipelines
- Experience with creating, querying and maintaining databases, particularly MySQL or PostgreSQL
- Advanced use of git version control
- Demonstrable experience in a clinical diagnostic department
- Experience in deploying production ready applications to support genetic diagnostic services
- Knowledge of bash and shell scripting
- Ability to work in a Unix/Linux environment
- Detailed knowledge of core computer service concepts
- Up to date knowledge of the relevant scientific literature
- Evidence of professional and personal development.
Desirable
- Experience usAdvanced knowledge of the Python programming language, and commonly used Python libraries and web frameworks (e.g. Django and Flask)ing docker for development
- Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)
- Experience testing python code e.g. using pytest
Skills/Abilities
Essential
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Ability to develop and maintain excellent communication and working relationships
- Advanced problem-solving skills
- Able to provide specialist advice to laboratory staff
- Able to present data at departmental and inter-departmental meetings
- Awareness of clinical significance of genetics findings and implications for patients
- Work to deadlines, operating autonomously and as part of a team
- Knowledge and understanding of ISO15189 accreditation standards and their application to a genomics laboratory
- Ability to write and follow bioinformatics protocols
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Employer details
Employer name
Great Ormond Street Hospital for Children NHS Foundation Trust
Address
Great Ormond Street Hospital for Children NHS Foundation Trust
Great Ormond Street Hospital
LondonLondon
WC1N 3JH
Employer's website
https://www.gosh.nhs.uk/ (Opens in a new tab)
