Guy's and St Thomas' NHS Foundation Trust

Clinical Trials Research Fellow

This job is now closed

Job summary

This post is to replace our long-standing clinical fellow, who has recently returned to clinical training. The CF Clinical Trials Team has an exciting and expanding clinical trials portfolio. The successful candidate will work alongside the multidisciplinary team. The post is ideally suited for a trainee with paediatric respiratory training wishing to a) gain a full understanding of the CF clinical trials pipeline, and b) become trained and experienced in all aspects of clinical trial conduct including Good Clinical Practice, Research Ethics, Informed Consent, specialised outcome measures (which may include sweat testing, nasal potential difference and lung clearance index). Adult respiratory medicine trainees will also be considered.

Note:

The above description is not exhaustive, and may be altered to meet the changing needs of the post and of the directorate. The post holder will be expected to be flexible and to co-operate in accordance with the changing requirements of the directorate and of the Trust.

The post is for 12 months in the first instance, but may be extended if for a candidate wishing to remain in post longer.

Main duties of the job

Focussing on clinical trials & research in cystic fibrosis, with possible opportunities for involvement in other Chronic Suppurative Lung Diseases i.e. bronchiectasis & primary ciliary dyskinesia.

The opportunity to gain experience of adult & paediatric respiratory medicine by attending clinics/ward rounds on a supernumerary basis. The chance to develop your own research/quality improvement projects & contribute to other departmental research. If undertaking such activities, we will support abstract submissions to national/international conferences for further exposure to CF research.

No on call; possible opportunity for ad hoc cover of absences by a suitable qualified/experienced post-holder.

You are encouraged to attend Adult & Paediatric departments regular teaching activities . There are weekly respiratory seminars run through the Respiratory Clinical Research Facility.

The National Heart and Lung Institute (NHLI) has excellent facilities for studying and an extensive library with all the current journals & textbooks. The NHLI is part of Imperial College, greatly enhancing the facilities available for studying and research.

Numerous postgraduate courses are held in the NHLI and the CF Department takes an active part. Postgraduate students are attached to the Department and receive tutorials and ward rounds from departmental members.

You are required to be fully registered with the General Medical Council and to produce such evidence as requested.

About us

Our Cystic Fibrosis Centre is one of the largest in Europe, caring for >800 paediatrics & adults with the disease. The team comprise both clinicians & clinical academics employed by Imperial College London. There is a vibrant & productive research focus working with and alongside clinical colleagues, in areas such as microbiology, advance lung physiology/ imaging, complex diagnoses & clinical trials of novel therapies.

As one of the highest performing member sites of the European Cystic Fibrosis Society Clinical Trials Network (https://www.ecfs.eu/ctn) and CF Trust-sponsored Clinical Trials Accelerator Platform, we offer opportunities for our patients, and those referred by other centres, to participate in a number of clinical trials (phase 1,2 & 3); including gene-based medicines, small molecule CFTR modulators, mucolytics, anti-microbials and anti-inflammatory agents. You will work in the Respiratory Clinical Research Facility (CRF) and will be closely aligned to paediatric & adult CF teams.

Clinical trial team membersCo-Leaders: Prof Jane Davies & Dr Nicholas SimmondsOther Principal Investigators: Drs Andrew Jones & Siobhan CarrClinical Trial Co-ordinators: Clare Saunders, Sophie Pinnell, Mary Abkir, x2 posts which we are currently appointing CRF: Geraldine Sloane (Mgr), Lyn Ambrose (Lab Mgr)Trials Pharmacists: Vibha Teli, Vivian WuR&D: Patrik PetterssonAdmin support: Gina Rivellini

Date posted

01 March 2024

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

Depending on experience salary appropriate to level of training

Contract

Fixed term

Duration

1 years

Working pattern

Full-time

Reference number

196-MED4373

Job locations

Royal Brompton Hospital

Sydney Street

London

SW3 6LR

Job description

Job responsibilities

Clinical trials support

Role includes:

Assisting the team in the identification of suitable clinical trial patients to approach and assessing eligibility
Studying for and obtaining Good Clinical Practice (GCP) Certification and Consent Training
Attending Investigator Meetings, Initiation visits for new trials and assisting with preparation for and conduct of monitoring/ close-out visits and regulatory inspections
Preparing for and attending monthly team review meetings
Performing clinical assessments adhering to trial protocols
Reviewing laboratory test results
Reviewing and grading adverse events; communicating closely with the consultants on these
Liaising with sponsors and Clinical Research Organisations

Clinical/research

Attend clinics and ward rounds on a supernumerary basis.
Opportunity to develop your own research/quality improvement projects and contribute to other research within the department.
Abstract submissions to national and international conferences for further exposure to CF related research.
Attend internal teaching activities and respiratory seminars.

Job description

Job responsibilities

Clinical trials support

Role includes:

Assisting the team in the identification of suitable clinical trial patients to approach and assessing eligibility
Studying for and obtaining Good Clinical Practice (GCP) Certification and Consent Training
Attending Investigator Meetings, Initiation visits for new trials and assisting with preparation for and conduct of monitoring/ close-out visits and regulatory inspections
Preparing for and attending monthly team review meetings
Performing clinical assessments adhering to trial protocols
Reviewing laboratory test results
Reviewing and grading adverse events; communicating closely with the consultants on these
Liaising with sponsors and Clinical Research Organisations

Clinical/research

Attend clinics and ward rounds on a supernumerary basis.
Opportunity to develop your own research/quality improvement projects and contribute to other research within the department.
Abstract submissions to national and international conferences for further exposure to CF related research.
Attend internal teaching activities and respiratory seminars.

Person Specification

Education and Qualifications

Essential

MBBS or equivalent

Desirable

GCP
MRCP or MRCPCH

Skills & Abilities - clinical

Essential

Technical and clinical skills required for adult or paediatric respiratory medicine
Shows an approach based on critical enquiry and evidence based medicine
Ability to organise self and others
Understanding of Informed Consent principles

Desirable

ALS/PALS/APLS

Skills & Abilities - research

Essential

Interest in, and an ability to initiate & conduct research
Attention to detail and meticulous record keeping

Desirable

Published research
Involvement in clinical trials

Personal Qualities

Essential

Builds a strong and effective relationship with patients, their parents and families and colleagues and gain in their confidence and trust
Is able to cope with pressure as well as adapt to constant change and new demands
Demonstrates honesty, commitment, and integrity

Other Requirements

Essential

Registration with GMC

Person Specification

Education and Qualifications

Essential

MBBS or equivalent

Desirable

GCP
MRCP or MRCPCH

Skills & Abilities - clinical

Essential

Technical and clinical skills required for adult or paediatric respiratory medicine
Shows an approach based on critical enquiry and evidence based medicine
Ability to organise self and others
Understanding of Informed Consent principles

Desirable

ALS/PALS/APLS

Skills & Abilities - research

Essential

Interest in, and an ability to initiate & conduct research
Attention to detail and meticulous record keeping

Desirable

Published research
Involvement in clinical trials

Personal Qualities

Essential

Builds a strong and effective relationship with patients, their parents and families and colleagues and gain in their confidence and trust
Is able to cope with pressure as well as adapt to constant change and new demands
Demonstrates honesty, commitment, and integrity

Other Requirements

Essential

Registration with GMC

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

Certificate of Sponsorship

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Guy's and St Thomas' NHS Foundation Trust

Address

Royal Brompton Hospital

Sydney Street

London

SW3 6LR

Employer's website

https://www.guysandstthomas.nhs.uk/careers/careers.aspx (Opens in a new tab)

Employer details

Employer name

Guy's and St Thomas' NHS Foundation Trust

Address

Royal Brompton Hospital

Sydney Street

London

SW3 6LR

Employer's website

https://www.guysandstthomas.nhs.uk/careers/careers.aspx (Opens in a new tab)