Job summary
Based in the adult NIHR Clinical Research Facility (CRF) at Guy's and St. Thomas' NHS Foundation Trust, this appointment provides an excellent opportunity for a doctor to gain experience of clinical research, including world-leading early phase trials, across a broad range of medical specialities within the supportive environment of a leading teaching and research hospital. The position provides the post holder with the opportunity to be involved in the testing of treatments and interventions that could shape the health care of tomorrow.
The CRF incorporates our Medicines and Healthcare products Regulatory Agency (MHRA) accredited Phase I unit, one of only three such facilities within the NHS. Supporting the activity of the phase I unit is a core component of the Junior CRF Research Physician role providing the post holder the opportunity to work with novel and advanced therapies (including cell and gene therapies) prior to market authorisation. As part of this work, the post holder will support risk assessments, developing and implementing critical risk mitigation strategies for new early phase studies; this will include trials employing advanced therapies under the oversight of first-in-human accredited investigators.
Main duties of the job
The post holder will work alongside experienced Principal Investigators (PI) within a multidisciplinary team and contribute to the clinical operations of our units. The post holder will provide medical support for patients and healthy volunteers participating in the clinical trials running on our unit. The post holder will work collaboratively with our management team to shape and guide the service as we expand the scope and breadth of the service. The post holder will be actively encouraged to contribute to the work of the UK Clinical Research Network (UKCRF) working groups and present relevant outcomes at national conferences.
The post would suit doctors aiming for a career in academic medicine and those looking for opportunities to engage in clinical research.
The post is for a 12-month period. The post will be appointed at an ST1-ST4 dependent on experience. The post is available as a full time position or a job-share arrangement.
We strongly encourage any interested applicants to contact us to arrange an informal visit to our facility.
About us
As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.
All our vacancies can be viewed on our website.
Our excellent benefits include final salary pension scheme. Please visit our website to find out more.
Equality of opportunity is our Policy. The Trust provides health services to a diverse community.
Job description
Job responsibilities
Detailed job description and personal specification can be downloaded below. Please contact Dr Henry Fok if you have any question.
Job description
Job responsibilities
Detailed job description and personal specification can be downloaded below. Please contact Dr Henry Fok if you have any question.
Person Specification
Qualifications and Training
Essential
- MBBS or equivalent with full valid GMC Registration and hold a licence to practise Recent ALS training allowing direct medical responsibility for human investigations in the UK
Desirable
- Postgraduate specialist qualification eg MRCP or equivalent.
Clinical Experience
Essential
- A minimum of 2 years post-registration experience. Experience of supervising / training others
Desirable
- Experience in the conduct of clinical pharmacology studies.
Knowledge and Skills
Essential
- Ability to work as an effective member of a multidisciplinary team Excellent interpersonal, verbal, and written communication skills. Experienced in the use MS Word, Excel, PowerPoint. Ability to discuss and appropriately escalate to the consultant(s) in charge the medical needs of patients referred to the CRF. Ability to learn and implement new study related clinical skills (including but not limited to skin and abdominal fat biopsies, VO2 max exercise testing, etc.).
Desirable
- Familiarity with principles of clinical research, including Good Clinical Practice, pharmacokinetics, human toxicology, statistics and pharmacodynamic assessment. Basic knowledge of statistics Competence in venous cannulation.
Research
Essential
- Understanding of the principles and applications of clinical research. Good understanding and experience of the regulatory environment for clinical trials and clinical research in the UK.
Desirable
- Evidence of original research
Management
Essential
- Evidence of understanding of the role of clinical management
Desirable
- Management training or qualification Evidence of leadership in the development of clinical services
Other
Essential
- Evidence of understanding of and adherence to the principles of Good Medical Practice set out by the General Medical Council Evidence of contribution to effective clinical audit and clinical risk management Ability to exercise initiative and work independently.
Desirable
- Experience in clinical guideline development Appraisal training
Person Specification
Qualifications and Training
Essential
- MBBS or equivalent with full valid GMC Registration and hold a licence to practise Recent ALS training allowing direct medical responsibility for human investigations in the UK
Desirable
- Postgraduate specialist qualification eg MRCP or equivalent.
Clinical Experience
Essential
- A minimum of 2 years post-registration experience. Experience of supervising / training others
Desirable
- Experience in the conduct of clinical pharmacology studies.
Knowledge and Skills
Essential
- Ability to work as an effective member of a multidisciplinary team Excellent interpersonal, verbal, and written communication skills. Experienced in the use MS Word, Excel, PowerPoint. Ability to discuss and appropriately escalate to the consultant(s) in charge the medical needs of patients referred to the CRF. Ability to learn and implement new study related clinical skills (including but not limited to skin and abdominal fat biopsies, VO2 max exercise testing, etc.).
Desirable
- Familiarity with principles of clinical research, including Good Clinical Practice, pharmacokinetics, human toxicology, statistics and pharmacodynamic assessment. Basic knowledge of statistics Competence in venous cannulation.
Research
Essential
- Understanding of the principles and applications of clinical research. Good understanding and experience of the regulatory environment for clinical trials and clinical research in the UK.
Desirable
- Evidence of original research
Management
Essential
- Evidence of understanding of the role of clinical management
Desirable
- Management training or qualification Evidence of leadership in the development of clinical services
Other
Essential
- Evidence of understanding of and adherence to the principles of Good Medical Practice set out by the General Medical Council Evidence of contribution to effective clinical audit and clinical risk management Ability to exercise initiative and work independently.
Desirable
- Experience in clinical guideline development Appraisal training
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
