University Hospital Southampton NHS Trust

Senior Clinical Fellow in Haematology (CAR-T fellow)

The closing date is 29 July 2025

Job summary

University Hospital Southampton NHS Foundation Trust is delighted to offer a fantastic opportunity to work with us.

This is a fixed term contract with the position commencing in the month of September 2025.

Please see below for detailed job description of the role.

Main duties of the job

This is a replacement appointment for a CAR-T fellow in Haematology, based at Southampton General Hospital.

The post has been developed to support the CAR-T cell programme, working closely with the Southampton Lymphoma Service and the Wessex Bone Marrow Transplantation and Cell Therapy Program (WBMT&CTP).

You will join the Department of Clinical Haematology and participate in the management of patients with haematological disorders undergoing CAR-T cell therapy (including ALL, Lymphoma and other indications as they arise). You will work within consultant-led subspecialty teams, alongside specialty registrars. There may be the option to contribute to the haematology on-call rota depending on experience and needs of the service.

Whilst the post is ideally suited to a haematology specialty trainee or equivalent, the post is open to individuals with at least MRCP Part 2, higher speciality qualification, or equivalent.

The posts can be tailored to fit the your needs, including if you're post-CCT or have undertaken haematology training oversees or wish to obtain specific subspecialty experience. You will be exposed to cell-therapy clinical trial activity, and research opportunities will be available.

About us

As one of the largest acute teaching Trusts in England, we offer learning and development opportunities to help you achieve the career you aspire to. UHS is rated 'Good' by the CQC and in the latest national NHS Staff Survey, we were in the top 10 acute trusts for staff engagement and for staff recommending the hospital as a place to work or receive care.

We support flexible working and will consider requests taking into account the needs of the service. UHS employees are able to access a range of NHS discounts, are entitled to a minimum of 35 days paid holiday (pro rata), and we offer a generous pension scheme.

Southampton is an attractive place to live and work situated on the south coast, with an international airport and direct trains to London. The New Forest National Park and beaches of the Jurassic coast are also right on our doorstep. The city offers living costs 20% lower than London and 14 schools rated outstanding by Ofsted.

Details

Date posted

15 July 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£65,048 to £73,992 a year Depending on experience

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

188-MB10725

Job locations

Southampton General Hospital

Tremona Road

Southampton

SO16 6YD


Job description

Job responsibilities

Southampton has a comprehensive research active Clinical Haematology department, incorporating Haematological Oncology, Stem Cell Transplantation and Cellular Therapy, Transfusion Medicine, Haemoglobinopathies, General and Immune Haematology and Haemostasis & Thrombosis services. The Haematology service is subspecialty based and provides clinical and laboratory service both to the local population in Southampton and South West Hampshire, as well as tertiary referrals for specialist opinions for complex cases and for a range of clinical trials.

The principal duties of the posts will include:

Review of patients referred for CAR-T cell therapy, in an outpatient or inpatient setting.

Liaison with referring teams, CAR-T consultants, and CAR-T coordination team in planning for apheresis, bridging, infusion, discharge, and post-CAR-T follow-up.

Management of patients undergoing CAR-T cell therapy in the inpatient and ambulatory setting, in collaboration with the subspecialty teams and supervising CAR-T consultants.

Referral to other specialty teams (e.g. intensive care, neurology, cardiology) as required to provide optimal care of patients undergoing CAR-T cell therapy.

Discussion of cases as appropriate at the Southampton lymphoma and leukaemia/myeloma MDTs, and the CAR-T MDT.

Active involvement with the development and expansion of the CAR-T service within the WBMT&CT, in collaboration with the subspecialty CAR-T leads.

Active involvement in the recruitment and management of patients within CAR-T clinical trials

Collaboration with other colleagues in the region through MDT and network-wide working

Development of regional CAR-T referral pathways in collaboration with CAR-T lead consultants

Participation in clinical governance activities including morbidity and mortality meetings and other committees as appropriate both within and external to the department.

Contribution to the audit activities of the WBMT&CT Programme and wider haematology department, including specialty regional and national audit programmes. Where possible, to participate in the collection and analysis of local data with a view to preparing and submitting papers for publication, and to contribute to the ongoing collection of real-world UK CAR-T data through the National CAR-T Clinical Panel (NCCP).

Undertaking of procedures relevant to haematology, including bone marrow biopsy, intrathecal chemotherapy, and tunnelled central catheter removal. Where necessary, appropriate training and supervision will be provided.

Engagement with the education programme, including attendance at regular educational meetings. Pre-CCT post-holders will be expected to maintain an educational portfolio mirroring their equivalent stage of training. Post-CCT fellows will be required to engage with the trusts existing appraisal system.

Cross-cover to other specialty teams within haematology during both planned and unplanned absence.

Education and Training Opportunities:

The haematology education and training programme was overhauled in 2021 following the launch of the JRCTB Haematology Curriculum. You will have access to the same training opportunities as the Specialist Registrars including being allocated an educational supervisor, study leave and self-development time.

There is a weekly Wessex-wide teaching programme encompassing clinical and laboratory haematology plus specific laboratory morphology sessions for more junior trainees to gain laboratory competencies. There are several regional training days each year.

There will be opportunity to take on Quality Improvement Projects and other clinical research activities dependent on your interests.

ADDITIONAL INFORMATION

Appointment will be made under local contractual terms and conditions of service for Trust appointed (non-training fellow doctors and dentists). Successful candidates will have an educational framework equivalent to training grade doctors, and there will be a named educational supervisor assigned at the start of the post. The opportunity for Continued Professional Development (CPD) is highly supported and encouraged by the Trust, with options available to take study leave. All licensed doctors must meet the GMC requirements for revalidation and there will be an annual appraisal to support this process.Grades for Trust appointed (non-training) fellows will be paid a basic salary at a nodal pay point linked to the grade, at the rate set out in the National Medical and Dental pay circular.Basic salary detailed below plus any additional remuneration (as applicable) for hours set out in the doctors work schedule (e.g. additional hours, weekend allowance, and any hours which attract enhanced pay)

Basic Salary MT04 £65,048 Basic Salary MT05 £73,992

Salary will be assessed based on experience and skills. Eligibility criteria for appointment to a Nodal Point 5;

Have a minimum of 6 years of Specialty training Hold relevant higher specialty exam (e.g FRCP, FRCA, FRCS) A portfolio of evidence that demonstrates they meet the criteria for progression (in line with the Curriculum for the speciality similar to deanery trainee)

Travelling expenses will not be paid for attending interview Please note that GMC registration (with a licence to practice) and right to work in the UK are essential for this role.

Successful applicants will already have GMC registration or will be able to demonstrate they are eligible.

Applicants requiring Tier 2 sponsorship should ensure they meet the Home Office application criteria prior to submitting an application.

Interviews will be held on 8th August 2025

Job Reference; 188-MB10725- This vacancy closes on or before 29th July 2025

Job description

Job responsibilities

Southampton has a comprehensive research active Clinical Haematology department, incorporating Haematological Oncology, Stem Cell Transplantation and Cellular Therapy, Transfusion Medicine, Haemoglobinopathies, General and Immune Haematology and Haemostasis & Thrombosis services. The Haematology service is subspecialty based and provides clinical and laboratory service both to the local population in Southampton and South West Hampshire, as well as tertiary referrals for specialist opinions for complex cases and for a range of clinical trials.

The principal duties of the posts will include:

Review of patients referred for CAR-T cell therapy, in an outpatient or inpatient setting.

Liaison with referring teams, CAR-T consultants, and CAR-T coordination team in planning for apheresis, bridging, infusion, discharge, and post-CAR-T follow-up.

Management of patients undergoing CAR-T cell therapy in the inpatient and ambulatory setting, in collaboration with the subspecialty teams and supervising CAR-T consultants.

Referral to other specialty teams (e.g. intensive care, neurology, cardiology) as required to provide optimal care of patients undergoing CAR-T cell therapy.

Discussion of cases as appropriate at the Southampton lymphoma and leukaemia/myeloma MDTs, and the CAR-T MDT.

Active involvement with the development and expansion of the CAR-T service within the WBMT&CT, in collaboration with the subspecialty CAR-T leads.

Active involvement in the recruitment and management of patients within CAR-T clinical trials

Collaboration with other colleagues in the region through MDT and network-wide working

Development of regional CAR-T referral pathways in collaboration with CAR-T lead consultants

Participation in clinical governance activities including morbidity and mortality meetings and other committees as appropriate both within and external to the department.

Contribution to the audit activities of the WBMT&CT Programme and wider haematology department, including specialty regional and national audit programmes. Where possible, to participate in the collection and analysis of local data with a view to preparing and submitting papers for publication, and to contribute to the ongoing collection of real-world UK CAR-T data through the National CAR-T Clinical Panel (NCCP).

Undertaking of procedures relevant to haematology, including bone marrow biopsy, intrathecal chemotherapy, and tunnelled central catheter removal. Where necessary, appropriate training and supervision will be provided.

Engagement with the education programme, including attendance at regular educational meetings. Pre-CCT post-holders will be expected to maintain an educational portfolio mirroring their equivalent stage of training. Post-CCT fellows will be required to engage with the trusts existing appraisal system.

Cross-cover to other specialty teams within haematology during both planned and unplanned absence.

Education and Training Opportunities:

The haematology education and training programme was overhauled in 2021 following the launch of the JRCTB Haematology Curriculum. You will have access to the same training opportunities as the Specialist Registrars including being allocated an educational supervisor, study leave and self-development time.

There is a weekly Wessex-wide teaching programme encompassing clinical and laboratory haematology plus specific laboratory morphology sessions for more junior trainees to gain laboratory competencies. There are several regional training days each year.

There will be opportunity to take on Quality Improvement Projects and other clinical research activities dependent on your interests.

ADDITIONAL INFORMATION

Appointment will be made under local contractual terms and conditions of service for Trust appointed (non-training fellow doctors and dentists). Successful candidates will have an educational framework equivalent to training grade doctors, and there will be a named educational supervisor assigned at the start of the post. The opportunity for Continued Professional Development (CPD) is highly supported and encouraged by the Trust, with options available to take study leave. All licensed doctors must meet the GMC requirements for revalidation and there will be an annual appraisal to support this process.Grades for Trust appointed (non-training) fellows will be paid a basic salary at a nodal pay point linked to the grade, at the rate set out in the National Medical and Dental pay circular.Basic salary detailed below plus any additional remuneration (as applicable) for hours set out in the doctors work schedule (e.g. additional hours, weekend allowance, and any hours which attract enhanced pay)

Basic Salary MT04 £65,048 Basic Salary MT05 £73,992

Salary will be assessed based on experience and skills. Eligibility criteria for appointment to a Nodal Point 5;

Have a minimum of 6 years of Specialty training Hold relevant higher specialty exam (e.g FRCP, FRCA, FRCS) A portfolio of evidence that demonstrates they meet the criteria for progression (in line with the Curriculum for the speciality similar to deanery trainee)

Travelling expenses will not be paid for attending interview Please note that GMC registration (with a licence to practice) and right to work in the UK are essential for this role.

Successful applicants will already have GMC registration or will be able to demonstrate they are eligible.

Applicants requiring Tier 2 sponsorship should ensure they meet the Home Office application criteria prior to submitting an application.

Interviews will be held on 8th August 2025

Job Reference; 188-MB10725- This vacancy closes on or before 29th July 2025

Person Specification

Qualifications, Training & Experience

Essential

  • MBBS or equivalent medical qualification
  • GMC registration with a licence to practise
  • MRCP Part 1 or higher specialty membership exam (or equivalent)
  • MRCP Part 2 or higher specialty membership exam (or equivalent
  • Appropriate knowledge base, and ability to apply sound clinical judgement to problems
  • Internal Medicine experience for at least 12 months OR Clinical Haematology experience for at least 6 months
  • Experience of out of hours and emergency care

Desirable

  • MRCP PACES
  • Higher degree
  • Experience of working as a doctor in the NHS
  • Internal medicine for at least 24 months
  • Clinical haematology experience for at least 12 months
  • Quality improvement or education project completion
  • Publications related to haematology
  • Presentations and/or teaching related to haematology
  • Experience of stem cell transplantation and cellular therapies

Aptitudes and skills

Essential

  • Evidence and ability to work effectively in multi-professional teams
  • Understanding of equality and diversity and how this affects patients, visitors and staff
  • Evidence and ability to communicate and liaise effectively with patients and colleagues (verbal and written communication skills in English).

Desirable

  • Evidence of participation in undergraduate and postgraduate teaching
  • Evidence of ability to work with indirect supervision in clinical haematology in both inpatient and outpatient settings
  • Evidence of understanding of principles of treatment for cancer and haematology patients

Living Trust Values

Essential

  • Patients First
  • Always Improving
  • Working Together
Person Specification

Qualifications, Training & Experience

Essential

  • MBBS or equivalent medical qualification
  • GMC registration with a licence to practise
  • MRCP Part 1 or higher specialty membership exam (or equivalent)
  • MRCP Part 2 or higher specialty membership exam (or equivalent
  • Appropriate knowledge base, and ability to apply sound clinical judgement to problems
  • Internal Medicine experience for at least 12 months OR Clinical Haematology experience for at least 6 months
  • Experience of out of hours and emergency care

Desirable

  • MRCP PACES
  • Higher degree
  • Experience of working as a doctor in the NHS
  • Internal medicine for at least 24 months
  • Clinical haematology experience for at least 12 months
  • Quality improvement or education project completion
  • Publications related to haematology
  • Presentations and/or teaching related to haematology
  • Experience of stem cell transplantation and cellular therapies

Aptitudes and skills

Essential

  • Evidence and ability to work effectively in multi-professional teams
  • Understanding of equality and diversity and how this affects patients, visitors and staff
  • Evidence and ability to communicate and liaise effectively with patients and colleagues (verbal and written communication skills in English).

Desirable

  • Evidence of participation in undergraduate and postgraduate teaching
  • Evidence of ability to work with indirect supervision in clinical haematology in both inpatient and outpatient settings
  • Evidence of understanding of principles of treatment for cancer and haematology patients

Living Trust Values

Essential

  • Patients First
  • Always Improving
  • Working Together

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

University Hospital Southampton NHS Trust

Address

Southampton General Hospital

Tremona Road

Southampton

SO16 6YD


Employer's website

https://www.uhs.nhs.uk/home.aspx (Opens in a new tab)


Employer details

Employer name

University Hospital Southampton NHS Trust

Address

Southampton General Hospital

Tremona Road

Southampton

SO16 6YD


Employer's website

https://www.uhs.nhs.uk/home.aspx (Opens in a new tab)


Employer contact details

For questions about the job, contact:

Consultant Haematologist

Dr Rob Lown

robert.lown@uhs.nhs.uk

Details

Date posted

15 July 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£65,048 to £73,992 a year Depending on experience

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

188-MB10725

Job locations

Southampton General Hospital

Tremona Road

Southampton

SO16 6YD


Supporting documents

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